Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
F2 / Prothrombin / Thrombin
coagulation factor II (thrombin)
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
| Gene Name: | coagulation factor II (thrombin) |
| Family/Subfamily: | Protease , Serine S1 |
| Synonyms: | F2, Prothrombin B-chain, Coagulation factor II, FACTOR II, Prothrombin, PT, RPRGL2, Serine protease, THPH1, Thrombin |
| Target Sequences: | NM_000506 NP_000497.1 P00734 |
Publications (3)
1
Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. Radulovic M, Yoon H, Wu J, Mustafa K, Scarisbrick IA. Neurobiology of disease. 2016 93:226-42. (WB; Human)
[Full Text Article]
[PubMed:27145117]
Related Antibodies: LS-C118750.
2
Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts. Clay T Cohen, Nancy A Turner, Joel L Moake. Scientific reports. 2020 Feb;10:2005. [Full Text Article]
[PubMed:32029851]
[PMC:PMC7005260]
3
Maternal plasma proteomics in a rat model of pregnancy complications reveals immune and pro-coagulant gene pathway activation. Tino W Sanchez, Bo Li, Christine Molinaro, Carlos A Casiano, Denise L Bellinger, Eugenia Mata-Greenwood. American journal of reproductive immunology (New York, N.Y. : 1989). 2020 February;83:e13205. [Full Text Article]
[PubMed:31677200]
[PMC:PMC8553409]
☰ Filters
Products
Antibodies
(211)
ELISA Kits
(42)
Proteins
(18)
Type
Cell-Based
(1)
Competitive EIA
(3)
Custom
(2)
Development Kit
(3)
Over-Expression Lysate
(2)
Primary
(211)
Recombinant
(16)
Sandwich
(29)
Sandwich CLIA
(4)
Target
F2 / Prothrombin / Thrombin
(271)
Reactivity
Human
(112)
Mouse
(78)
Rat
(92)
Bat
(3)
Bovine
(10)
Chicken
(1)
Cow
(1)
Dog
(3)
Gibbon
(3)
Guinea pig
(1)
Monkey
(6)
Orangutan
(3)
Pig
(11)
Rabbit
(8)
Application
IHC
(15)
IHC-P
(11)
WB
(171)
ELISA
(61)
ICC
(1)
IE
(6)
IF
(8)
Inhb
(1)
IP
(1)
Peptide-ELISA
(4)
RIA
(1)
RNAi
(1)
Host
rabbit
(120)
mouse
(47)
burro
(1)
rat
(1)
sheep
(42)
Product Group
DevKit DuoPlus
(3)
IHCPlus
(8)
Isotype
IgG
(90)
IgG1
(3)
IgG1,k
(1)
IgG2a
(6)
IgG2b,k
(8)
Clonality
monoclonal mc
(48)
polyclonal pc
(163)
Clone
1B7
(1)
318
(1)
AHP-5013
(1)
Ca-Pro 20
(2)
OTI5B11
(2)
OTI5G10
(2)
Format
12 x 8-Well Microstrips
(4)
96-Well Microplate
(8)
96-Well Strip Plate
(27)
Antibody Pair and Standard
(3)
APC
(13)
APC Conjugated
(14)
Biotin Conjugated
(26)
Carrier-free
(2)
Cy3 Conjugated
(13)
Cy7 Conjugated
(13)
FITC Conjugated
(22)
HRP Conjugated
(26)
PE Conjugated
(14)
Preservative Free
(3)
Unconjugated
(83)
Epitope
aa44-200
(34)
aa324-617
(10)
aa325-618
(10)
aa201-323
(8)
aa201-324
(8)
aa44-198
(8)
aa130-179
(4)
aa44-622
(4)
Internal
(2)
250-330 aa, Internal
(1)
AP2, Cleaved-Arg327
(1)
Gly724
(1)
aa278-327
(1)
aa391-440
(1)
aa396-445
(1)
aa46-79
(1)
aa600-612
(1)
Publications
No
(268)
Yes
(3)
Sample Type
Adherent Cell Cultures
(1)
Cell Culture Media
(2)
Cell Culture Supernatants
(1)
Plasma
(28)
Serum
(32)
Tissue Extracts
(2)
Tissue Homogenates
(6)
Tag
6His, N-terminus
(2)
6His-SUMO, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(7)
His, N-Terminal
(1)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Human
(9)
Mouse
(4)
Rat
(4)
Source
293T Cells
(1)
E. coli
(11)
HEK 293 Cells
(2)
Human Cells
(1)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(1)
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (aa391-440) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal Antibody
Bovine, Human
ELISA, IHC, IHC-P
Unconjugated
250 µg/$485
F2 / Prothrombin / Thrombin Mouse anti-Human Monoclonal (AHP-5013) Antibody
Human
ELISA, Inhb, WB
Unconjugated
100 µg/$397
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$427; 1 mg/$572; 10 mg/$3,208
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$427; 1 mg/$572; 10 mg/$3,408
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IE
HRP Conjugated
200 µg/$657
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal (HRP) Antibody
Bovine
ELISA, IE
HRP Conjugated
200 µg/$665
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal Antibody
Human
Unconjugated
10 mg/$515
F2 / Prothrombin / Thrombin Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
200 µg/$657
F2 / Prothrombin / Thrombin Sheep anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.5 mg/$485
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Bovine
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Microplate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
E. coli
6His, N-terminus
67.6 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F2 / Prothrombin / Thrombin Sheep anti-Bovine Polyclonal Antibody
Bovine
ELISA
Unconjugated
1 mg/$459
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal (Gly724) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
E. coli
His-T7
20.9 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
F2 / Prothrombin / Thrombin Rabbit anti-Rat Polyclonal (aa130-179) Antibody
Rat
WB
Unconjugated
100 µl/$424
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
F2 / Prothrombin / Thrombin Sheep anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
1 ml/$424
F2 / Prothrombin / Thrombin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$427; 1 ml/$572; 10 ml/$3,497
Viewing 1-25
of 271
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
