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F13B / TGase

coagulation factor XIII, B polypeptide

F13B / TGase is coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

Gene Name: coagulation factor XIII, B polypeptide
Synonyms: F13B, Transglutaminase B chain, FXIIIB, TGASE
Target Sequences: NM_001994 NP_001985.2 P05160

☰ Filters
Antibodies (40)
ELISA Kits (15)
Proteins (4)
Competitive EIA (2)
Over-Expression Lysate (2)
Primary (40)
Recombinant (2)
Sandwich (12)
Sandwich CLIA (1)
F13B / TGase (59)
Human (32)
Mouse (26)
Rat (3)
Bovine (3)
Chicken (1)
Chimpanzee (3)
Dog (3)
Guinea pig (3)
Monkey (5)
Porcine (1)
Rabbit (1)
IHC (10)
IHC-P (6)
WB (32)
ELISA (17)
ICC (1)
IF (5)
Peptide-ELISA (2)
rabbit (34)
mouse (6)
Product Group
IHCPlus (1)
IgG (20)
IgG1 (6)
monoclonal mc (6)
polyclonal pc (34)
OTI1A3 (2)
OTI2D4 (2)
OTI2H10 (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (12)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (22)
aa21-208 (8)
aa151-179 (7)
aa357-661 (6)
aa216-265 (4)
30-110 aa, N-terminal (1)
Internal (1)
N-Terminus (1)
aa61-110 (1)
No (59)
Plasma (11)
Serum (9)
Tissue Homogenates (3)
Urine (1)
His (2)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Human Cells (1)
Low endotoxin level (1)
F13B / TGase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F13B / TGase ELISA Kit
Select
Sandwich
96-Well Microplate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
F13B / TGase Antibody - Western blot of Factor XIII B antibody
Select
F13B / TGase Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
F13B / TGase Antibody - Immunohistochemistry analysis of paraffin-embedded human heart tissue, using F13B Antibody. The picture on the right is blocked with the synthesized peptide.
Select
F13B / TGase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
F13B / TGase Antibody - Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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F13B / TGase Rabbit anti-Human Polyclonal (aa216-265) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
F13B / TGase Antibody - Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
F13B / TGase Rabbit anti-Human Polyclonal (aa216-265) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
F13B / TGase Antibody - Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
F13B / TGase Rabbit anti-Human Polyclonal (aa216-265) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
F13B / TGase Antibody - Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
F13B / TGase Rabbit anti-Human Polyclonal (aa216-265) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
F13B / TGase Antibody - Immunohistochemistry analysis of paraffin-embedded human heart tissue, using F13B Antibody. The picture on the right is blocked with the synthesized peptide.
Select
F13B / TGase Rabbit anti-Human Polyclonal (aa61-110) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
F13B / TGase Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human heart tissue using F13B antibody.
Select
F13B / TGase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
F13B / TGase Antibody - Immunofluorescent analysis of Factor XIII B staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 ??C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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F13B / TGase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
F13B / TGase Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver, antibody was diluted at 1:200.
Select
F13B / TGase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
F13B / TGase Antibody - Immunohistochemical analysis of Factor XIII B staining in human liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
F13B / TGase Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
Select
F13B / TGase Rabbit anti-Human Polyclonal (aa151-179) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa151-179) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa151-179) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa151-179) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa151-179) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa151-179) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
F13B / TGase Antibody - Western Blot Positive WB detected in: 293 whole cell lysate All Lanes: F13B antibody at 4.17µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 76 KDa Observed band size: 76 KDa
Select
F13B / TGase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
F13B / TGase Antibody - Western blot analysis F13B using COS7 whole cells lysates
Select
F13B / TGase Rabbit anti-Human Polyclonal Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
F13B / TGase Antibody - Western blot of F13B / TGase antibody.
Select
F13B / TGase Rabbit anti-Mouse Polyclonal (aa21-208) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553
F13B / TGase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B.
Select
F13B / TGase Mouse anti-Human Monoclonal (aa357-661) (OTI2H10) Antibody
Human
WB
Unconjugated
100 µl/$434
F13B / TGase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B.
Select
F13B / TGase Mouse anti-Human Monoclonal (aa357-661) (OTI1A3) Antibody
Human
WB
Unconjugated
100 µl/$434
F13B / TGase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY F13B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-F13B.
Select
F13B / TGase Mouse anti-Human Monoclonal (aa357-661) (OTI2D4) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 59 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).