F12 / Factor XII

coagulation factor XII (Hageman factor)

F12 / Factor XII is coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

☰ Filters

Products

Antibodies (98)

ELISA Kits (32)

Proteins (8)

Type

Competitive EIA (1)

Custom (3)

Over-Expression Cell Culture Supernatant (1)

Primary (98)

Recombinant (7)

Sandwich (24)

Sandwich CLIA (4)

Target

F12 / Factor XII (138)

Reactivity

Human (88)

Mouse (34)

Rat (10)

Chicken (2)

Gibbon (3)

Guinea pig (1)

Monkey (5)

Pig (5)

Porcine (1)

Primate (1)

Rabbit (2)

Sheep (1)

more less

Application

IHC (15)

IHC-P (7)

WB (76)

ELISA (51)

Func (1)

ICC (1)

ID (2)

IE (3)

IF (3)

IP (1)

Peptide-ELISA (2)

RIA (1)

more less

Host

rabbit (62)

mouse (23)

goat (7)

sheep (6)

Product Group

IHCPlus (3)

Isotype

IgG (51)

IgG1 (9)

IgG1,k (8)

IgG1,l (2)

IgG2a (1)

IgG2a,k (1)

IgG2b (2)

Clonality

monoclonal mc (21)

polyclonal pc (77)

Clone

11B9-4F8 (1)

11E3-C11D9D12 (1)

15G5-H8C11 (1)

20B2-5B5 (2)

20C8-6F9F1 (1)

22H6-H12C12 (1)

23E10-D12A11 (1)

3A3 (1)

5B5 (1)

6G8-D7 (1)

B7C9 (1)

C6B7 (1)

OTI1H5 (2)

OTI2D12 (2)

OTI5A6 (2)

more less

Format

12 x 8-Well Microstrips (5)

96-Well Microplate (4)

96-Well Strip Plate (23)

APC (2)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (11)

Carrier-free (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (9)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (59)

more less

Epitope

aa352-587 (8)

aa400-615 (8)

aa7-34 (7)

aa9-38 (7)

aa73-372 (6)

N-Terminus (5)

10-90 aa, N-terminal (1)

300-380 aa, Internal (1)

Internal (1)

aa1-50 (1)

heavy chain, Cleaved-Arg372 (1)

heavy chain, Cleaved-Ile20 (1)

more less

Publications

No (137)

Yes (1)

Sample Type

Plasma (23)

Serum (18)

Tissue Homogenates (4)

Tag

6His, N-terminus (2)

GST (2)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (2)

Species

Human (5)

Mouse (1)

Pig (2)

Source

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Yeast (1)

Purification

Purified (4)

Select

IHC-plus™ F12 / Factor XII Antibody LS-B4239

(4.0) Rating

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.5 mg/$460

Select

IHC-plus™ F12 / Factor XII Antibody LS-B2649

(4.0) Rating

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ F12 / Factor XII Antibody LS-B3044

(4.0) Rating

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, IHC, IHC-P, IP

Format:

Unconjugated

Price:

50 µg/$460

Select

F12 / Factor XII Antibody LS-C150723

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Primate, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

Select

F12 / Factor XII Antibody (N-Terminus) LS-C413031

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

F12 / Factor XII Antibody LS-C23417

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Func

Format:

Unconjugated

Price:

250 µg/$1,453

Select

F12 / Factor XII Antibody LS-C331638

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F21335

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10418

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$521

Select

Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10441

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.1 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$896

Select

F12 / Factor XII Antibody (clone C6B7) LS-C83330

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (C6B7) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

250 µg/$587

Select

Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F4434

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$764

Select

F12 / Factor XII Antibody (clone 5B5) LS-C828162

Antibody:

F12 / Factor XII Mouse anti-Mouse Polyclonal (5B5) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$505; 1 mg/$3,108

Select

F12 / Factor XII Antibody LS-C147235

Antibody:

F12 / Factor XII Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID

Format:

Unconjugated

Price:

1 ml/$438

Select

F12 / Factor XII Antibody (clone B7C9) LS-C83329

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (B7C9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

250 µg/$587

Select

F12 / Factor XII Antibody (clone 3A3) LS-C197181

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (3A3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

F12 / Factor XII Antibody LS-C128941

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 mg/$459

Select

F12 / Factor XII Antibody (aa73-372, clone OTI5A6) LS-C794013

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (aa73-372) (OTI5A6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

F12 / Factor XII Antibody (aa9-38) LS-C159582

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (aa9-38) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

F12 / Factor XII Antibody LS-C681904

Antibody:

F12 / Factor XII Rabbit anti-Pig Polyclonal Antibody

Reactivity:

Pig

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

F12 / Factor XII Antibody (aa400-615, Biotin) LS-C684873

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (aa400-615) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217

Select

Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F15049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

F12 / Factor XII Antibody LS-C109226

Antibody:

F12 / Factor XII Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$327; 1 ml/$405

Select

F12 / Factor XII Antibody (aa9-38, FITC) LS-C208918

Antibody:

F12 / Factor XII Rabbit anti-Human Polyclonal (aa9-38) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

F12 / Factor XII Antibody (aa73-372, clone OTI2D12) LS-C794012

Antibody:

F12 / Factor XII Mouse anti-Human Monoclonal (aa73-372) (OTI2D12) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Viewing 1-25 of 138 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.