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EXO1

exonuclease 1

5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Gene Name: exonuclease 1
Synonyms: EXO1, Exonuclease 1, Exonuclease I, HEX1, HExoI, EXOI, HExo1
Target Sequences: NM_003686

☰ Filters
Antibodies (53)
Proteins (6)
Over-Expression Lysate (2)
Primary (53)
Recombinant (4)
EXO1 (59)
Human (45)
Mouse (21)
Rat (19)
Bovine (3)
Chimpanzee (6)
Gibbon (3)
Guinea pig (6)
Monkey (3)
Pig (3)
Rabbit (6)
Zebrafish (3)
IHC (2)
WB (48)
ChrIP (1)
ELISA (10)
ICC (2)
IF (7)
IP (3)
Peptide-ELISA (3)
rabbit (50)
mouse (2)
goat (1)
IgG (14)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (51)
10C180 (1)
APC (3)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (6)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (6)
HRP Conjugated (7)
PE Conjugated (3)
Unconjugated (22)
aa1-250 (8)
C-Terminus (4)
aa74-123 (4)
N-Terminus (2)
aa747-846 (2)
30-110 aa, N-terminal (1)
Lys86 (1)
aa1-30 (1)
aa372-383 (1)
aa61-110 (1)
aa725-775 (1)
aa796-846 (1)
No (59)
GST, N-terminus (1)
His-T7 (1)
His-T7, N-terminus (2)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
EXO1 Antibody - Immunohistochemistry of paraffin-embedded human esophageal cancer tissue.
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
EXO1 Antibody - Western blot of Exo1 antibody
Select
EXO1 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
EXO1 Antibody - Western blot of anti-EXO1 Antibody in NCI-H460 cell line lysates (35 ug/lane). EXO1 (arrow) was detected using the purified antibody.
Select
EXO1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ICC, IF, WB
Unconjugated
400 µl/$393
Select
EXO1 Mouse anti-Human Monoclonal (aa747-846) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
100 µl/$904
Select
EXO1 Mouse anti-Human Monoclonal (aa747-846) (Azide-free) (10C180) Antibody
Human
ELISA, WB
Unconjugated, Azide-free
100 µg/$705
EXO1 Antibody - EXO1 antibody Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
EXO1 Rabbit anti-Human Polyclonal (aa74-123) Antibody
Human
WB
Unconjugated
100 µl/$424
EXO1 Antibody - Western Blot; Sample: Recombinant EXO1, Human.
Select
EXO1 Rabbit anti-Human Polyclonal (aa1-250) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
EXO1 Antibody - Immunofluorescent analysis of EXO1 staining in A431 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Select
EXO1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ChrIP, ICC, IF, WB
Unconjugated
100 µl/$299
EXO1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
93.9 kDa
20 µg/$150
EXO1 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using EXO1 antibody.
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
EXO1 Antibody - Immunofluorescence analysis of A549 cells, using EXO1 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
EXO1 Rabbit anti-Human Polyclonal (aa61-110) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
EXO1 Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
EXO1 Antibody - Western blot of Exo1 (K86) pAb in extracts from raw264.7 cells.
Select
EXO1 Rabbit anti-Human Polyclonal (Lys86) Antibody
Mouse, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
EXO1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$379
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
EXO1 Rabbit anti-Human Polyclonal (aa725-775) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
EXO1 Rabbit anti-Human Polyclonal (aa796-846) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
EXO1 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using EXO1 Antibody at dilution of 1:100
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
EXO1 Antibody - Antibody (0.2 ug/ml) staining of A549 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
EXO1 Goat anti-Human Polyclonal (aa372-383) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
EXO1 Antibody
Select
EXO1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
EXO1 Antibody
Select
EXO1 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse, Rat, Human
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
EXO1 Antibody
Select
EXO1 Rabbit anti-Mouse Polyclonal (Cy3) Antibody
Mouse, Rat, Human
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
EXO1 Antibody - EXO1 antibody Western Blot of A549. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
EXO1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
EXO1 Rabbit anti-Human Polyclonal Antibody
Human
IP
Unconjugated
100 µl/$749
Viewing 1-25 of 59 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).