ETK / BMX

BMX non-receptor tyrosine kinase

Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells.

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Antibodies (60)

Proteins (9)

ELISA Kits (8)

Type

Cell-Based (2)

Cell-Based Phosphorylation (2)

Custom (1)

Over-Expression Lysate (4)

Primary (60)

Recombinant (5)

Sandwich (3)

Target

ETK / BMX (77)

Reactivity

Human (58)

Mouse (53)

Rat (5)

Bovine (1)

Dog (1)

Monkey (4)

Pig (1)

Application

IHC (37)

IHC-P (15)

WB (57)

ELISA (22)

ICC (5)

IF (19)

IP (1)

Peptide-ELISA (7)

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rabbit (56)

mouse (4)

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IHCPlus (2)

Isotype

IgG (29)

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IgG2b,k (1)

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monoclonal mc (4)

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aa209-446 (8)

aa287-523 (8)

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N-Terminus (2)

aa65-280 (2)

20-100 aa (1)

30-110 aa, N-terminal (1)

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aa11-60 (1)

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Sample Type

Adherent Cell Cultures (4)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Mouse (1)

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293T Cells (2)

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IHC-plus™ ETK / BMX Antibody (aa11-60) LS-B5666

(4.0) Rating

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa11-60) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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ETK / BMX Antibody (N-Terminus) LS-C358926

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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ETK / BMX Antibody (aa532-581) LS-C117805

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa532-581) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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ETK / BMX Antibody (aa212-242) LS-C99167

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa212-242) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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IHC-plus™ ETK / BMX Antibody (N-Terminus) LS-B14562

(4.0) Rating

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

ETK / BMX Antibody (phospho-Tyr566) LS-C358432

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr566) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$315

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ETK / BMX Antibody (aa287-523) LS-C375044

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa287-523) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345

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ETK / BMX Antibody (aa287-523, Biotin) LS-C689628

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa287-523) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479

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ETK / BMX Antibody (aa287-523, APC) LS-C719868

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa287-523) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689

• Unconjugated
• Biotin
• APC

• Unconjugated
• Biotin
• APC

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ETK / BMX Antibody (Tyr566) LS-C822138

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (Tyr566) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ETK / BMX Antibody (phospho-Tyr40) LS-C822004

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr40) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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Human ETK / BMX (Sandwich ELISA) ELISA Kit - LS-F35485

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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ETK / BMX Antibody (phospho-Tyr566) LS-C198938

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr566) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

ETK / BMX Antibody (C-Terminus) LS-C358925

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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ETK / BMX Antibody (phospho-Tyr40) LS-C351871

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr40) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$315

Select

ETK / BMX Antibody LS-C822774

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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ETK / BMX Antibody LS-C808661

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ETK / BMX Antibody (phospho-Tyr566) LS-C808531

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr566) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ETK / BMX Antibody LS-C417558

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

ETK / BMX Antibody (phospho-Tyr40) LS-C198937

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (pTyr40) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

ETK / BMX Antibody (20-100 aa) LS-C381488

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (20-100 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

ETK / BMX Antibody (510-590 aa) LS-C382304

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (510-590 aa) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

ETK / BMX Antibody (30-110 aa, N-terminal) LS-C382306

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

ETK / BMX Antibody (aa65-280) LS-C375327

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (aa65-280) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

ETK / BMX Antibody (Lys35) LS-C176412

Antibody:

ETK / BMX Rabbit anti-Human Polyclonal (Lys35) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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