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ESR2 / ER Beta
estrogen receptor 2 (ER beta)
Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. ER beta is phosphorylated upon ligand activation and binds to target DNA as a homodimer. At least eight alternatively spliced isoforms of ER beta have been documented, many of which show tissue-specific expression patterns. A novel and functionally distinct isoform of human ER beta (ER beta548), which includes an extended amino-terminal domain has been identified recently by Wilkinson et al. 2002. ER beta has been suggested to affect carcinogenesis in smooth muscle, urogenital tract, breast, and colonic tissues.
| Gene Name: | estrogen receptor 2 (ER beta) |
| Family/Subfamily: | NHR , NR3 Steroid receptor |
| Synonyms: | ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4 |
| Target Sequences: | NM_001437 NP_001428.1 Q92731 |
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ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa82-131) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa71-120) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ESR2 / ER Beta Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa94-118) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
E. coli
His
63.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
ESR2 / ER Beta Rabbit anti-Mouse Polyclonal (aa512-530) Antibody
Mouse
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$848
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (ERb455) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Ready-to-Use) (ERb455) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (ERb455) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (ESR2/686) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Ready-to-Use) (ESR2/686) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (ESR2/686) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (NR3Gb-1) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Ready-to-Use) (NR3Gb-1) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (NR3Gb-1) Antibody
Mouse, Sheep, Rat, Pig, Horse, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
ESR2 / ER Beta Rabbit anti-Mouse Polyclonal (aa101-115) Antibody
Mouse, Rat, Bat, Human, Monkey
GS, ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$858
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
WB
Unconjugated
100 µl/$424
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa369-397) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa369-397) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa369-397) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa369-397) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ESR2 / ER Beta Rabbit anti-Human Polyclonal (aa369-397) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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