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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ESR2 / ER Beta Antibody (aa481‑495, clone 57/3) LS‑C188258
Note: This antibody replaces LS-C121785
Antibody
ER Beta antibody LS-C188258 is an unconjugated mouse monoclonal antibody to human ER Beta (ESR2). Validated for IHC.
Catalog
Size
Price
LS-C188258-100
100 µg (1 mg/ml)
Unavailable

Popular ESR2 / ER Beta Products

Antibody
Species: Mouse
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot
Anti-ER-Beta antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B945 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bat, Bovine, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: Western blot
Immunofluorescence of HeLa cells, using Estrogen Receptor-beta (Ab-105) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot

Product Description

ER Beta antibody LS-C188258 is an unconjugated mouse monoclonal antibody to human ER Beta (ESR2). Validated for IHC.
About ESR2 / ER Beta
Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. Q92731 NM_001437 NP_001428.1

ESR2 Antibody, ESTRB Antibody, ER Beta Antibody, ERbeta Antibody, ER-BETA Antibody, ESR-BETA Antibody, ESRB Antibody, Estrogen receptor 2 (ER beta) Antibody, NR3A2 Antibody, Estrogen receptor beta Antibody, Estrogen receptor beta 4 Antibody


Specifications

Target
Human ESR2 / ER Beta
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [57/3]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • Western blot
Immunogen
ESR2 / ER Beta antibody was raised against synthetic peptide derived from the C terminus of the human estrogen receptor beta 2 isomer, C-GMKMETLLPEATMEQ. Percent identity by BLAST analysis: Human (100%); Marmoset (93%).
Epitope
aa481-495
Specificity
Recognizes the estrogen receptor beta 2 isoform. No cross-reactivity is seen with estrogen receptor beta 1 isoform. Estrogen receptor beta 2 is expressed in cell nuclei of a range of human tissues including the ovary, placenta, testis and vas deferens.
Presentation
PBS, 0.09% sodium azide
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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