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ERI1 / HEXO

exoribonuclease 1

RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

Gene Name: exoribonuclease 1
Synonyms: ERI1, 3 exoribonuclease, 3'HEXO, 3-5 exonuclease ERI1, 3HEXO, 3-5 exoribonuclease 1, 3EXO, Exoribonuclease 1, Histone mRNA 3-exonuclease 1, Protein 3hExo, THEX1, Eri-1 homolog, HEXO, Three prime mRNA exonuclease 1
Target Sequences: NM_153332 NP_699163.2 Q8IV48

☰ Filters
Antibodies (44)
Proteins (7)
Over-Expression Lysate (2)
Primary (44)
Recombinant (5)
ERI1 / HEXO (51)
Human (36)
Mouse (16)
Rat (11)
Bovine (3)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (5)
Rabbit (6)
IHC (4)
IHC-P (2)
WB (41)
ELISA (11)
IF (3)
Peptide-ELISA (2)
rabbit (42)
mouse (2)
IgG (25)
IgG2b (2)
monoclonal mc (2)
polyclonal pc (42)
OTI1B3 (2)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (16)
aa80-109 (7)
aa231-280 (4)
aa29-78 (4)
230-310 aa, Internal (1)
aa249-298 (1)
No (51)
GST (1)
His-T7, N-terminus (2)
Myc-DDK (Flag) (4)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
ERI1 / HEXO Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
ERI1 / HEXO Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ERI1 mouse monoclonal antibody.
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ERI1 / HEXO Mouse anti-Human Monoclonal (OTI1B3) Antibody
Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ERI1 / HEXO Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ERI1 mouse monoclonal antibody.
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ERI1 / HEXO Mouse anti-Human Monoclonal (Carrier-free) (OTI1B3) Antibody
Rat, Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ERI1 / HEXO Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ERI1 / HEXO Rabbit anti-Human Polyclonal (230-310 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ERI1 / HEXO Antibody - Western blot analysis of the lysates from HUVECcells using ERI1 antibody.
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ERI1 / HEXO Rabbit anti-Human Polyclonal (aa249-298) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
100 µl/$289
ERI1 / HEXO Antibody - B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal (aa231-280) Antibody
Human
WB
Unconjugated
100 µl/$397
ERI1 / HEXO Antibody - MCF7 cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ERI1 / HEXO Rabbit anti-Human Polyclonal (aa29-78) Antibody
Human
WB
Unconjugated
100 µl/$424
ERI1 / HEXO Antibody - ERI1 Antibody western blot of 293 cell line lysates (35 ug/lane). The ERI1 antibody detected the ERI1 protein (arrow).
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ERI1 / HEXO Rabbit anti-Human Polyclonal (aa80-109) Antibody
Human
WB
Unconjugated
400 µl/$393
ERI1 / HEXO Antibody - Western Blot; Sample: Recombinant protein.
Select
ERI1 / HEXO Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 51 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).