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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERCC3 / XPB Antibody (clone 2327C4a) LS‑C184639
XPB antibody LS-C184639 is an unconjugated mouse monoclonal antibody to human XPB (ERCC3). Validated for DB and ICC.
Catalog
Size
Price
LS-C184639-50
50 µg (0.1 mg/ml)
Unavailable

Popular ERCC3 / XPB Products

Anti-ERCC3 / XPB antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1693 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-ERCC3 / XPB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2815 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Immunofluorescence of paraformaldehyde-fixed HeLa, using XPB antibody at 1:200 dilution.
Species: Human
Applications: ICC, Immunofluorescence, Western blot
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Species: Human, Orangutan, Mouse, Rat, Bovine
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation

Product Description

XPB antibody LS-C184639 is an unconjugated mouse monoclonal antibody to human XPB (ERCC3). Validated for DB and ICC.
About ERCC3 / XPB
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. P19447 NM_000122 NP_000113.1

ERCC3 Antibody, BTF2 Antibody, GTF2H Antibody, RAD25 Antibody, TFIIH p89 Antibody, TFIIH Antibody, XPB Antibody, BTF2 p89 Antibody, XPBC Antibody, TFIIH 89 kDa subunit Antibody


Specifications

Target
Human ERCC3 / XPB
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [2327C4a]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ICC (2 - 100 µg/ml)
  • Dot Blot
Immunogen
ERCC3 / XPB antibody was raised against recombinant Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 3 (Xeroderma Pigmentosum Group B Complementing) (Ercc3).
Specificity
Human ERCC3
Presentation
PBS, pH 7.4, 1% BSA, 0.05% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of immunized recombinant protein using ERCC3 antibody.
Western blot of immunized recombinant protein using ERCC3 antibody.

Western blot

Western blot of immunized recombinant protein using ERCC3 antibody.
Western blot of immunized recombinant protein using ERCC3 antibody.

Western blot

Western blot of immunized recombinant protein using ERCC3 antibody.
Western blot of immunized recombinant protein using ERCC3 antibody.

Western blot

Western blot of immunized recombinant protein using ERCC3 antibody.
Western blot of immunized recombinant protein using ERCC3 antibody.


Requested From: 
Date Requested: 6/21/2018

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