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Anti-ERCC2 / XPD Antibody IHC-plus™ LS-B3814

Note: This antibody replaces LS-C108170

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ERCC2 / XPD Antibodies

Anti-ERCC2 / XPD Antibody IHC-plus™ LS-B3814
Goat Polyclonal to Human ERCC2 / XPD
Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ERCC2 / XPD Antibody (aa1-406, Biotin) LS-C225444
Mouse Monoclonal (IgG1) to Human ERCC2 / XPD
Human
Western blot, ELISA
Biotin Conjugated
Anti-ERCC2 / XPD Antibody (aa1-406, Azide-free, HRP) LS-C225447
Mouse Monoclonal (IgG1) to Human ERCC2 / XPD
Human
Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human ERCC2 / XPD
Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Pig, Rabbit
IHC - Paraffin
Unconjugated

Details

Human ERCC2 / XPD
Goat
Human, Monkey, Mouse, Bat, Bovine, Dog, Hamster, Pig, Rabbit (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (3.75 µg/ml)

Specificity and Use

ERCC2 / XPD antibody was raised against synthetic peptide from human ERCC2 / XPD. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Elephant, Panda, Dog, Bat, Bovine, Rabbit, Pig (100%); Rat, Opossum, Salmon, Stickleback, Seq squirt, Sea anemone, Capsaspora (92%); Zebrafish (83%).
Human ERCC2 / XPD.
Immunohistochemistry: LS-B3814 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3814 was determined to be 3.75ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About ERCC2 / XPD

P18074 NM_000400 CAA36463.1

ERCC2 Antibody, COFS2 Antibody, EM9 Antibody, XPD Antibody, TFIIH p80 Antibody, BTF2 p80 Antibody, TTD Antibody, XPDC Antibody, CXPD Antibody, TFIIH 80 kDa subunit Antibody

ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation.

Immunohistochemistry

Immunohistochemistry
Anti-ERCC2 / XPD antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3814 concentration 3.75 ug/ml.
 

Requested From: United States
Date Requested: 12/3/2016

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