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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERCC2 / XPD Antibody LS‑C6711
XPD antibody LS-C6711 is an unconjugated mouse monoclonal antibody to XPD (ERCC2). Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C6711-50
50 µg (0.25 mg/ml)
$515

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Product Description

XPD antibody LS-C6711 is an unconjugated mouse monoclonal antibody to XPD (ERCC2). Validated for ELISA.

Specifications

Target
ERCC2 / XPD
Synonyms
ERCC2, COFS2, EM9, XPD, TFIIH p80, BTF2 p80, TTD, XPDC, CXPD, TFIIH 80 kDa subunit
Host
Mouse
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA (1:4000)
Immunogen
ERCC2 / XPD antibody was raised against peptide of ERCC2 (80kD subunit of TFIIH).
Specificity
Recognizes ERCC2 subunit of TFIIH and it has no cross reaction with ERCC3 subunit.
Usage
Suitable for use in ELISA. ELISA: 1:4000.
Presentation
PBS, pH 7.2, 40% Glycerol
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About ERCC2 / XPD
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. P18074 NM_000400 CAA36463.1


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Requested From: United States
Date Requested: 10/19/2018

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