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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERBB3 / HER3 Antibody (clone 2F12) LS‑C87931
Antibody
HER3 antibody LS-C87931 is an unconjugated mouse monoclonal antibody to HER3 (ERBB3) from human, mouse, rat and other species. Validated for IP and WB.
Catalog
Size
Price
LS-C87931-0.1
0.1 ml
Unavailable
LS-C87931-0.5
0.5 ml
Unavailable
LS-C87931-1
1 ml
Unavailable

Popular ERBB3 / HER3 Products

Anti-HER3 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2126 concentration 5 ug/ml.
Species: Human, Monkey, Rat, Bat, Hamster, Horse, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Immunofluorescence, Immunoprecipitation, Flow Cytometry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Anti-HER3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3896 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-HER3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6035 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

HER3 antibody LS-C87931 is an unconjugated mouse monoclonal antibody to HER3 (ERBB3) from human, mouse, rat and other species. Validated for IP and WB.
About ERBB3 / HER3
ERBB3 / HER3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. P21860 NM_001982 NP_001973.2

ERBB3 Antibody, C-erbB-3 Antibody, C-erbB3 Antibody, ErbB-3 Antibody, HER3 Antibody, p85-sErbB3 Antibody, p45-sErbB3 Antibody, MDA-BF-1 Antibody, ErbB3-S Antibody, LCCS2 Antibody, p180-ErbB3 Antibody


Specifications

Target
Rat ERBB3 / HER3
Host
Mouse
Reactivity
Rat, Human, Mouse, Bovine (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [2F12]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified. Also available Azide-free.
Applications
  • Western blot (1 µg/ml)
  • Immunoprecipitation (1 µg/ml)
  • (applications tested for the base form of this product only)
Failed Applications
  • IHC - Paraffin
Immunogen
ERBB3 / HER3 antibody was raised against recombinant rat c-erbB-3/HER-3 oncoprotein.
Specificity
aa1295-1323
Presentation
10mM PBS, pH 7.4, with 0.2% BSA and 0.09% Sodium Azide
Storage
Stable for 2 years when stored at 2-8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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