ERBB2 / HER2

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization.In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.

☰ Filters

Products

Antibodies (181)

Proteins (41)

ELISA Kits (23)

Type

Cell-Based (1)

Cell-Based Phosphorylation (4)

Custom (2)

Over-Expression Lysate (5)

Primary (181)

Recombinant (36)

Sandwich (15)

Sandwich CLIA (1)

Target

ERBB2 / HER2 (245)

Reactivity

Human (172)

Mouse (49)

Rat (54)

Bovine (2)

Chicken (1)

Dog (8)

Hamster (2)

Horse (3)

Monkey (8)

Pig (2)

Application

IHC (81)

IHC-Fr (11)

IHC-P (44)

WB (133)

Flo (22)

Bind (4)

ELISA (44)

EM (1)

Func (4)

ICC (1)

IF (43)

IP (12)

Peptide-ELISA (8)

PMA (8)

SDS-PAGE (8)

more less

Host

rabbit (90)

mouse (85)

goat (2)

human (1)

mouse-balb/c (1)

rat (2)

Product Group

IHCPlus (5)

PathPlus Cancer (5)

PathPlus Cancer Pathology (5)

Isotype

IgG (58)

IgG,k (1)

IgG1 (28)

IgG1 + IgG2b (1)

IgG1,k (2)

IgG2a (16)

IgG2a,k (10)

IgG2b (15)

IgG2b,k (4)

Clonality

monoclonal mc (92)

polyclonal pc (85)

recombinant monoclonal rmc (4)

Clone

002 (1)

006 (1)

07 (1)

11H9 (1)

12K88 (1)

1423CT594.76.52 (1)

1J5 (1)

205 (1)

2F1 (1)

2KRI7-2 (2)

3B1 (1)

3B5 (1)

3C9 (1)

40 (1)

4D5-8 (trastuzumab) (2)

4E1 (1)

5J297 (1)

6C2 (1)

6C2B12,9B9D8 (1)

8B5D4C1 (1)

9B9D8 (1)

9G6 (1)

ABT-Her2 (1)

AHC0142 (1)

CB11 (1)

ERBB2/2452 (2)

ERBB2/2453 (2)

ERBB2/3092 (3)

G002.1 (1)

HRB2/258 (1)

HRB2/718 (1)

ICR55 (1)

N28 (1)

OTI11A7 (2)

OTI12G4 (1)

OTI1A12 (1)

OTI1C5 (1)

OTI1D9 (1)

OTI2A1 (1)

OTI2G9 (1)

OTI3F11 (1)

OTI4F10 (1)

OTI4F6 (1)

OTI4G10 (1)

OTI4G7 (1)

OTI5A3 (1)

OTI5C3 (1)

OTI5C4 (1)

OTI5F6 (1)

OTI6F3 (1)

OTI6G9 (1)

OTI6H10 (1)

OTI6H9 (1)

OTI7C2 (1)

OTI9G2 (1)

PN2A (1)

RBT-HER2 (2)

SP3 (1)

UMAB33 (2)

UMAB34 (2)

UMAB35 (2)

UMAB36 (2)

more less

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (7)

96-Well Strip Plate (15)

APC (5)

APC Conjugated (6)

Azide-free (5)

Biotin Conjugated (7)

BSA-free (5)

Carrier-free (26)

Concentrated (2)

Cy3 Conjugated (5)

Cy7 Conjugated (5)

FITC Conjugated (6)

HRP Conjugated (5)

PE Conjugated (7)

Preservative Free (7)

Ready-to-Use (5)

Unconjugated (140)

more less

Epitope

aa676-1255 (31)

aa376-578 (16)

aa377-579 (8)

aa380-582 (6)

pTyr1248 (4)

aa21-52 (3)

pTyr1112 (3)

pTyr877 (3)

Amino Acid: 750-987 (2)

Cytoplasmic Domain (2)

Extracellular Domain (2)

aa1-652 (2)

aa1200-C-term (2)

erbB-2 (Her-2/neu) (2)

Ab-686 (1)

Internal (1)

N-Terminus (1)

aa1243-1255 (1)

aa182-194 (1)

aa23-419 (1)

aa23-652 (1)

aa23-653 (1)

aa531-559 (1)

aa641-690 (1)

p1221/1222 (1)

p1248 (1)

p686 (1)

p877 (1)

pThr686 (1)

pTyr1139 (1)

pTyr1222,pTyr1221 (1)

more less

Publications

No (244)

Yes (1)

Sample Type

Adherent Cell Cultures (5)

Cell Culture Supernatants (3)

Cell Lysates (1)

Plasma (14)

Serum (14)

Tissue Homogenates (8)

Tag

6His, C-terminus (4)

6His, N-terminus (3)

DDK (Flag)-His, C-terminus (1)

DDK,C-terminus (4)

Fc (1)

Fc, C-terminus (3)

Fc-AVI, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His,C-terminus (7)

His-GST (2)

His-GST, N-terminus (1)

His-T7 (1)

Human IgG Fc, C-terminus (2)

Myc-DDK (Flag) (6)

more less

Species

Human (28)

Mouse (5)

Rat (6)

Source

293T Cells (2)

Baculovirus (1)

CHO Cells (1)

E. coli (7)

HEK 293 Cells (18)

Human (1)

Human Cells (4)

Mammalian Cells (2)

Sf9 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (21)

Biologically Active

Biologically active (4)

Select

IHC-plus™ ERBB2 / HER2 Antibody (N-Terminus) LS-A9396

Fast Shipping

(4.0) Rating

Antibody:

ERBB2 / HER2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Bovine, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

Select

IHC-plus™ ERBB2 / HER2 Antibody (clone 3B5) LS-B7205

(4.0) Rating

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (3B5) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

PathPlus™ ERBB2 / HER2 Antibody (aa1243-1255) LS-B2133

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

ERBB2 / HER2 Rabbit anti-Human Polyclonal (aa1243-1255) Antibody

Reactivity:

Mouse, Dog, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$615

Select

ERBB2 / HER2 Antibody (clone HRB2/718) LS-C357930

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (HRB2/718) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-Fr

Format:

Unconjugated

Price:

100 µg/$574

Select

ERBB2 / HER2 Antibody (clone ICR55) LS-C11576

Antibody:

ERBB2 / HER2 Rat anti-Human Monoclonal (ICR55) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

25 µg/$285; 0.2 mg/$486

Select

ERBB2 / HER2 Antibody (aa1200-C-term) LS-C286320

Antibody:

ERBB2 / HER2 Rabbit anti-Human Polyclonal (aa1200-C-term) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

ERBB2 / HER2 Antibody (clone 5J297, FITC) LS-C533753

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (FITC) (5J297) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$1,064

Select

ERBB2 / HER2 Antibody (clone 3B1) LS-C133884

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (3B1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

ERBB2 / HER2 Antibody (aa23-652) LS-C128811

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (aa23-652) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$860

Select

ERBB2 / HER2 Antibody (aa23-653, clone 12K88) LS-C182844

Antibody:

ERBB2 / HER2 Rat anti-Mouse Monoclonal (aa23-653) (12K88) Antibody

Reactivity:

Mouse

Applications:

Flo

Format:

Unconjugated

Price:

100 µg/$919

Select

ERBB2 / HER2 Antibody (clone 1423CT594.76.52) LS-C356286

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (1423CT594.76.52) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ERBB2 / HER2 Antibody (Extracellular Domain, clone N28) LS-C85340

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (Extracellular Domain) (N28) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

100 µg/$928

Select

ERBB2 / HER2 Antibody (aa676-1255, clone OTI11A7) LS-C337488

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (aa676-1255) (OTI11A7) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

ERBB2 / HER2 Antibody (clone 9G6) LS-C150520

Antibody:

ERBB2 / HER2 Mouse-Balb/c anti-Human Monoclonal (9G6) Antibody

Reactivity:

Human

Applications:

EM, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$424

Select

ERBB2 / HER2 Antibody (Internal, clone CB11, Concentrated) LS-C202461

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (Internal) (Concentrated) (CB11) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated, Concentrated

Price:

1 ml/$1,006

Select

Human ERBB2 / HER2 Protein (Recombinant 6His, N-terminus) (aa23-652) - LS-G20710

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

73.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human ERBB2 / HER2 (Sandwich ELISA) ELISA Kit - LS-F5037

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

Select

ERBB2 / HER2 Antibody LS-C97503

Antibody:

ERBB2 / HER2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human ERBB2 / HER2 Protein (Recombinant 6His, N-terminus) (Thr23-Thr652) - LS-G26960

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

100 kDa

Price:

10 µg/$289; 50 µg/$360; 100 µg/$432

Select

ERBB2 / HER2 Antibody (clone HRB2/258, Azide-free, BSA-free) LS-C389696

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (HRB2/258) Antibody

Reactivity:

Rat, Human

Applications:

Flo, IF, IHC, IHC-Fr

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

Select

ERBB2 / HER2 Antibody (aa641-690) LS-C119532

Antibody:

ERBB2 / HER2 Rabbit anti-Human Polyclonal (aa641-690) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

ERBB2 / HER2 Antibody (erbB-2 (Her-2/neu), clone 4D5-8 (trastuzumab)) LS-C777444

Antibody:

ERBB2 / HER2 Human anti-Human Recombinant Monoclonal (erbB-2 (Her-2/neu)) (4D5-8 (trastuzumab)) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC

Format:

Unconjugated

Price:

0.2 mg/$540

Select

ERBB2 / HER2 Antibody (phospho-Tyr1248, clone PN2A) LS-C85334

Antibody:

ERBB2 / HER2 Mouse anti-Human Monoclonal (pTyr1248) (PN2A) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$942

Select

ERBB2 / HER2 Antibody (aa182-194) LS-C305886

Antibody:

ERBB2 / HER2 Goat anti-Human Polyclonal (aa182-194) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

Select

ERBB2 / HER2 Antibody (Extracellular Domain, clone SP3) LS-C95808

Antibody:

ERBB2 / HER2 Rabbit anti-Human Monoclonal (Extracellular Domain) (SP3) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

0.1 ml/$341; 0.5 ml/$795; 1 ml/$1,137

Viewing 1-25 of 245 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.