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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERBB2 / HER2 Antibody (clone 3B5) IHC‑plus™ LS‑B7205
Note: This antibody replaces LS-C149088
HER2 antibody LS-B7205 is an unconjugated mouse monoclonal antibody to HER2 (ERBB2) from human, mouse, rat and other species. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7205-50
50 µg (1 mg/ml)
Unavailable

Popular ERBB2 / HER2 Products

Antibody
Species: Human
Applications: Immunofluorescence, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human, Monkey, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation
Formalin-fixed, paraffin-embedded breast carcinoma stained with peroxidase conjugate and AEC chromogen. Note membrane staining of tumor cells.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Human
Applications: Western blot, ELISA
Anti-ERBB2 / HER2 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5935 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA

Product Description

HER2 antibody LS-B7205 is an unconjugated mouse monoclonal antibody to HER2 (ERBB2) from human, mouse, rat and other species. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
About ERBB2 / HER2
Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). P04626 NM_004448 NP_004439.2

ERBB2 Antibody, C-erb B2/neu protein Antibody, CD340 Antibody, HER2 Antibody, Herstatin Antibody, MLN 19 Antibody, HER-2 Antibody, Neu Antibody, NGL Antibody, Proto-oncogene c-ErbB-2 Antibody, Proto-oncogene Neu Antibody, CD340 antigen Antibody, MLN19 Antibody, p185erbB2 Antibody, TKR1 Antibody


Specifications

Target
Human ERBB2 / HER2
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [3B5]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • IHC - Frozen
  • Western blot (1:250 - 1:1000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ERBB2 / HER2 antibody was raised against a synthetic peptide from the C-terminus of human c-erbB-2 protein
Specificity
Sequence is identical in rat Neu protein. Reacts equally well with the wild as well as the mutant (oncogenic) form c-erbB-2 protein but preferentially recognizes the unphosphorylated form of c-erbB-2 protein.
Presentation
PBS containing 0.09% sodium azide.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +
Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +

Immunohistochemistry

Immunohistochemistry on paraffin section of human breast carcinoma
Immunohistochemistry on paraffin section of human breast carcinoma

Immunohistochemistry

Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.
Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +
Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +

Immunohistochemistry

Immunohistochemistry on paraffin section of human breast carcinoma
Immunohistochemistry on paraffin section of human breast carcinoma

Immunohistochemistry

Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.
Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +
Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +

Immunohistochemistry

Immunohistochemistry on paraffin section of human breast carcinoma
Immunohistochemistry on paraffin section of human breast carcinoma

Immunohistochemistry

Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.
Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +
Immunohistochemistry on paraffin section of human Mamma tumor Her2Neu +

Immunohistochemistry

Immunohistochemistry on paraffin section of human breast carcinoma
Immunohistochemistry on paraffin section of human breast carcinoma

Immunohistochemistry

Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.
Anti-ERBB2 / HER2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7205 concentration 10 ug/ml.


Requested From: 
Date Requested: 6/19/2018

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