Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3B5] (IgG1) to Human ERBB2 / HER2
Human, Monkey, Mouse, Rat
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Human ERBB2 / HER2
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [3B5]
Protein G purified
IHC - Paraffin (10 µg/ml)
IHC - Frozen
Western blot (1:250 - 1:1000)
Specificity and Use
ERBB2 / HER2 antibody was raised against a synthetic peptide from the C-terminus of human c-erbB-2 protein
Sequence is identical in rat Neu protein. Reacts equally well with the wild as well as the mutant (oncogenic) form c-erbB-2 protein but preferentially recognizes the unphosphorylated form of c-erbB-2 protein.
PBS containing 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
ERBB2 Antibody, C-erb B2/neu protein Antibody, CD340 Antibody, HER2 Antibody, Herstatin Antibody, MLN 19 Antibody, HER-2 Antibody, Neu Antibody, NGL Antibody, Proto-oncogene c-ErbB-2 Antibody, Proto-oncogene Neu Antibody, CD340 antigen Antibody, MLN19 Antibody, p185erbB2 Antibody, TKR1 Antibody
Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs).