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Anti-ERBB2 / HER2 Antibody (C-Terminus, clone SPM495) IHC-plus™ LS-B2778

Note: This antibody replaces LS-C50349

Ordering

Wt. Vol. Conc. Price
50 µg - 0.2 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ERBB2 / HER2 Antibodies

Anti-ERBB2 / HER2 Antibody (Extracellular Domain, clone 9G6.10) LS-C85336
Mouse Monoclonal [clone 9G6.10] (IgG1) to Human ERBB2 / HER2
Human
Immunofluorescence, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-ERBB2 / HER2 Antibody (clone SP3) LS-C88826
Rabbit Monoclonal [clone SP3] (IgG) to Human ERBB2 / HER2
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ERBB2 / HER2 Antibody (aa23-652) LS-C128811
Mouse Monoclonal (IgG2b) to Human ERBB2 / HER2
Human
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone SPM495] (IgG1,k) to Human ERBB2 / HER2
Human, Monkey, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Human ERBB2 / HER2
Mouse
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [SPM495]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (20 µg/ml)
  • Western blot

Specificity and Use

ERBB2 / HER2 antibody was raised against synthetic peptide corresponding to C-terminus of human c-erbB2 protein.
C-Terminus
Immunohistochemistry: LS-B2778 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2778 was determined to be 20 ug/ml.

Packaging

10 mM PBS, pH 7.4, BSA, sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About ERBB2 / HER2

P04626 NM_004448 NP_004439.2

ERBB2 Antibody, C-erb B2/neu protein Antibody, CD340 Antibody, HER2 Antibody, Herstatin Antibody, MLN 19 Antibody, HER-2 Antibody, Neu Antibody, NGL Antibody, Proto-oncogene c-ErbB-2 Antibody, Proto-oncogene Neu Antibody, CD340 antigen Antibody, MLN19 Antibody, p185erbB2 Antibody, TKR1 Antibody

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs).

Immunohistochemistry

Immunohistochemistry
Anti-ERBB2 / HER2 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2778 concentration 20 ug/ml.
 

Requested From: United States
Date Requested: 12/2/2016

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