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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ER Alpha / Estrogen Receptor Antibody (Gly161) LS‑C176013
Estrogen Receptor antibody LS-C176013 is an unconjugated rabbit polyclonal antibody to human Estrogen Receptor (ER Alpha). Validated for IHC and WB.
Catalog
Size
Price
LS-C176013-100
100 µl
Unavailable

Popular ER Alpha / Estrogen Receptor Products

Anti-Estrogen Receptor antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1470 concentration 10 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Bovine, Human, Mouse, Rat, Rabbit
Applications: Immunoprecipitation, Gel shift
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note intense nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note intense nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Estrogen Receptor antibody LS-C176013 is an unconjugated rabbit polyclonal antibody to human Estrogen Receptor (ER Alpha). Validated for IHC and WB.
About ER Alpha / Estrogen Receptor
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. P03372 NM_000125 NP_000116.2

ESR1 Antibody, Era Antibody, ERalpha Antibody, Estrogen receptor Antibody, Estradiol receptor Antibody, ER-alpha Antibody, Estrogen receptor 1 Antibody, NR3A1 Antibody, ER Antibody, ESR Antibody, ESRA Antibody, Estrogen receptor alpha Antibody


Specifications

Target
Human ER Alpha / Estrogen Receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Gly161 of human ER / Estrogen Receptor
Epitope
Gly161
Specificity
Human ER / Estrogen Receptor
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.
Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.

Immunohistochemistry

IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.
Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.

Immunohistochemistry

IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.
Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.

Immunohistochemistry

IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of Estrogen Receptor- (G161) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.
Western blot of Estrogen Receptor- (G161) pAb in extracts from MCF7 cells treated with EGF.


Requested From: 
Date Requested: 6/25/2018

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