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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ER Alpha / Estrogen Receptor Antibody (clone TE111.5D11, Biotin) LS‑C88069
Antibody
Estrogen Receptor antibody LS-C88069 is a biotin-conjugated mouse monoclonal antibody to Estrogen Receptor (ER Alpha) from human, mouse, rat and other species. Validated for Block, GS, IP and WB.
Catalog
Size
Price
LS-C88069-100
100 µl
Unavailable
LS-C88069-500
500 µl
Unavailable
LS-C88069-1000
1000 µl
Unavailable

Popular ER Alpha / Estrogen Receptor Products

Anti-Estrogen Receptor antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1470 concentration 10 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Antibody
Species: Bovine, Human, Mouse, Rat, Rabbit
Applications: Immunoprecipitation, Gel shift
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note intense nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note intense nuclear staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells.
Species: Human, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Estrogen Receptor antibody LS-C88069 is a biotin-conjugated mouse monoclonal antibody to Estrogen Receptor (ER Alpha) from human, mouse, rat and other species. Validated for Block, GS, IP and WB.
About ER Alpha / Estrogen Receptor
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. P03372 NM_000125 NP_000116.2

ESR1 Antibody, Era Antibody, ERalpha Antibody, Estrogen receptor Antibody, Estradiol receptor Antibody, ER-alpha Antibody, Estrogen receptor 1 Antibody, NR3A1 Antibody, ER Antibody, ESR Antibody, ESRA Antibody, Estrogen receptor alpha Antibody


Specifications

Target
Human ER Alpha / Estrogen Receptor
Host
Mouse
Reactivity
Human, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit, Sheep, Chicken (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [TE111.5D11]
Conjugations
Biotin. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation
  • Blocking
  • Gel shift
  • (applications tested for the base form of this product only)
Immunogen
35kDa, C-terminal fragment (aa 302-595) of human ER expressed in E. coli.
Specificity
aa 302-553
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
10mM PBS, pH 7.4, with 0.2% BSA and 0.09% Sodium Azide
Storage
Stable for 2 years when stored at 2-8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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