EPHA8 / EPH Receptor A8

EPH receptor A8

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.

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Products

Antibodies (10)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (10)

Recombinant (3)

Target

EPHA8 / EPH Receptor A8 (15)

Reactivity

Human (10)

Mouse (5)

Rat (4)

Chicken (1)

Application

WB (10)

ELISA (4)

Host

rabbit (6)

mouse (4)

Isotype

IgG (2)

IgG1 (4)

Clonality

monoclonal mc (4)

polyclonal pc (6)

Clone

13B255 (1)

9A12D8 (2)

Format

Unconjugated (10)

Epitope

aa70-150 (2)

Amino Acid: 70-150 (1)

Publications

No (15)

Tag

6His, C-terminus (1)

DDK (Flag)-His, C-terminus (1)

Fc, C-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Human (2)

Low Endotoxin Level

Low endotoxin level (2)

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EPHA8 / EPH Receptor A8 Antibody LS-C496921

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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EPHA8 / EPH Receptor A8 Antibody (aa70-150, clone 13B255) LS-C183472

Antibody:

EPHA8 / EPH Receptor A8 Mouse anti-Human Monoclonal (aa70-150) (13B255) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$688

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EPHA8 / EPH Receptor A8 Antibody (aa70-150, clone 9A12D8) LS-C171426

Antibody:

EPHA8 / EPH Receptor A8 Mouse anti-Human Monoclonal (aa70-150) (9A12D8) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 ml/$393

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EPHA8 / EPH Receptor A8 Antibody LS-C812456

Antibody:

EPHA8 / EPH Receptor A8 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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EPHA8 / EPH Receptor A8 Antibody LS-C665381

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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EPHA8 / EPH Receptor A8 Antibody (Amino Acid: 70-150, clone 9A12D8) LS-C758552

Antibody:

EPHA8 / EPH Receptor A8 Mouse anti-Human Monoclonal (Amino Acid: 70-150) (9A12D8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$518

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EPHA8 / EPH Receptor A8 Antibody LS-C760886

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Chicken, Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

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EPHA8 / EPH Receptor A8 Antibody LS-C760894

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

EPHA8 / EPH Receptor A8 Antibody LS-C760924

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

EPHA8 / EPH Receptor A8 Antibody LS-C761142

Antibody:

EPHA8 / EPH Receptor A8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

Select

Human EPHA8 / EPH Receptor A8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88068

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

108.1 kDa

Price:

20 µg/$215

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Human EPHA8 / EPH Receptor A8 Protein (Recombinant 6His, C-terminus) - LS-G146117

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.4 kDa

Price:

10 µg/$308; 50 µg/$502

Select

Human EPHA8 / EPH Receptor A8 Protein (Recombinant Fc, C-terminus) - LS-G146148

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

83.5 kDa

Price:

10 µg/$308; 50 µg/$502

Select

EPHA8 / EPH Receptor A8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111112

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

108.1 kDa

Price:

100 µg/$710

Select

Human EPHA8 / EPH Receptor A8 Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142216

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

60 kDa

Price:

20 µg/$1,107

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