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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EnvR / ERV3 Antibody (aa313‑323) IHC‑plus™ LS‑B7407 Best Seller
Note: This antibody replaces LS-C139689
ERV3 antibody LS-B7407 is an unconjugated goat polyclonal antibody to human ERV3 (EnvR). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7407-50
50 µg (0.5 mg/ml)
Unavailable

Popular EnvR / ERV3 Products

Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

ERV3 antibody LS-B7407 is an unconjugated goat polyclonal antibody to human ERV3 (EnvR). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
About EnvR / ERV3
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. Q14264 NP_001007254.2

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Specifications

Target
Human EnvR / ERV3
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3.75 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:4000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EnvR / ERV3 antibody was raised against synthetic peptide C-PQDNFTLTASS from an internal region of human ERV3 (NP_001007254.2). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan (100%); Monkey (91%).
Blocking Peptide
LS-E27531 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B7407. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa313-323
Specificity
Human ERV3.
Usage
Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Preliminary experiments gave an approx 30kD band in Human Placenta lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 67.9kD according to NP_001007254.2. The 30kD band was successfully blocked by incubation with the immunizing peptide.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.
Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.
Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.
Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.

Immunohistochemistry

Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.
Anti-ERV3 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7407 concentration 3.75 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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