Endostatin

collagen, type XVIII, alpha 1

Endostatin is the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

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Antibodies (83)

ELISA Kits (31)

Proteins (13)

Type

Competitive EIA (3)

Custom (1)

Development Kit (1)

Primary (83)

Recombinant (13)

Sandwich (25)

Sandwich CLIA (1)

Target

Endostatin (127)

Reactivity

Human (81)

Mouse (51)

Rat (19)

Bovine (1)

Chicken (1)

Dog (1)

Application

IHC (33)

IHC-Fr (1)

IHC-P (11)

WB (67)

Flo (2)

ELISA (31)

ICC (10)

IF (5)

IP (8)

Peptide-ELISA (3)

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rabbit (70)

mouse (13)

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DevKit DuoPlus (1)

IHCPlus (5)

Isotype

IgG (32)

IgG1 (3)

IgG2a (2)

IgG2b (1)

Clonality

monoclonal mc (13)

polyclonal pc (70)

Clone

1837.46 (1)

1837-46 (1)

KT3 (1)

KT58 (1)

KT60 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (6)

96-Well Strip Plate (22)

Antibody Pair and Standard (1)

APC (4)

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Azide-free (2)

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FITC Conjugated (7)

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PE Conjugated (7)

Unconjugated (38)

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Epitope

aa1072-1271 (8)

aa1572-1754 (8)

aa1591-1774 (8)

aa1311-1339 (7)

aa237-263 (7)

C-Terminus (3)

1270-1350 aa, C-terminal (1)

770-850 aa, Internal (1)

Internal (1)

aa1301-1350 (1)

aa52-114 (1)

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Publications

No (126)

Yes (1)

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Breast Milk (1)

Cell Culture Supernatants (12)

Cell Lysates (5)

Cell Supernatant (1)

Plasma (30)

Serum (30)

Tissue Homogenates (12)

Tag

6His, C-terminus (2)

His (2)

His, N-Terminal (2)

His-GST (1)

His-T7 (1)

Species

Human (7)

Mouse (4)

Rat (2)

Source

293F Cells (1)

E. coli (6)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Yeast (3)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (5)

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IHC-plus™ Endostatin Antibody (clone 1837.46) LS-B2229

(4.0) Rating

Antibody:

Endostatin Mouse anti-Mouse Monoclonal (1837.46 ) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$635

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IHC-plus™ Endostatin Antibody LS-B8215

(5.0) Rating

(1) Publication(s)

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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Endostatin Antibody (Biotin) LS-C104550

Antibody:

Endostatin Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IHC-plus™ Endostatin Antibody (C-Terminus) LS-B2163

(4.0) Rating

Antibody:

Endostatin Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Endostatin Antibody (C-Terminus) LS-C65320

Antibody:

Endostatin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$657

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Endostatin Antibody LS-C23046

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$533; 100 µl/$832

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IHC-plus™ Endostatin Antibody (aa801-850) LS-B5686

(4.0) Rating

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa801-850) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$460

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Endostatin Antibody (clone KT60) LS-C193522

Antibody:

Endostatin Mouse anti-Human Monoclonal (KT60) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$437

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Rat Endostatin (Competitive EIA) ELISA Kit - LS-F6296

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.23 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$893

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Endostatin Antibody (aa237-263) LS-C166920

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa237-263) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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Endostatin Antibody (Internal) LS-C358951

Antibody:

Endostatin Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Bovine, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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Mouse Endostatin (Sandwich ELISA) ELISA Kit - LS-F10528

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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IHC-plus™ Endostatin Antibody LS-B12823

(4.0) Rating

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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Endostatin Antibody LS-C372541

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136

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Endostatin Antibody (aa1311-1339) LS-C166919

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa1311-1339) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Endostatin Antibody LS-C121201

Antibody:

Endostatin Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$862

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Endostatin Antibody LS-C416222

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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Human Endostatin Protein (Recombinant His-T7) (aa1572-1754) - LS-G14809

Source:

E. coli

Tag:

His-T7

Molecular Weight:

23.9 kDa

Price:

10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866

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Endostatin Antibody (770-850 aa, Internal) LS-C382806

Antibody:

Endostatin Rabbit anti-Human Polyclonal (770-850 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Endostatin Antibody LS-C823478

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

Endostatin Antibody (aa1311-1339) LS-C320512

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa1311-1339) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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Endostatin Antibody (aa1311-1339, FITC) LS-C208513

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa1311-1339) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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Endostatin Antibody (aa1311-1339, APC) LS-C208512

Antibody:

Endostatin Rabbit anti-Human Polyclonal (aa1311-1339) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• APC

• Unconjugated
• FITC
• APC

Select

Endostatin Antibody LS-C665346

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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Endostatin Antibody LS-C800275

Antibody:

Endostatin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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