Endonuclease G / ENDOG

endonuclease G

The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (endoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndooG also cleaves DNA in vitro.

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Antibodies (55)

Proteins (6)

ELISA Kits (2)

Type

Native (1)

Over-Expression Lysate (2)

Primary (55)

Recombinant (3)

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Target

Endonuclease G / ENDOG (63)

Reactivity

Human (48)

Mouse (29)

Rat (32)

Bat (3)

Chicken (3)

Chimpanzee (3)

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Peptide-ELISA (2)

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rabbit (48)

mouse (7)

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IHCPlus (2)

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IgG (25)

IgG1 (6)

Clonality

monoclonal mc (6)

polyclonal pc (49)

Clone

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aa1-294 (8)

aa16-290 (8)

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aa61-110 (1)

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Cell Lysates (2)

Tissue Homogenates (2)

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GST (1)

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Source

293T Cells (1)

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Purification

Purified (2)

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Endonuclease G / ENDOG Antibody LS-C8

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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Endonuclease G / ENDOG Antibody LS-C408231

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IHC-plus™ Endonuclease G / ENDOG Antibody (clone 7F2D7) LS-B14747

(4.0) Rating

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (7F2D7) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Endonuclease G / ENDOG Antibody LS-C766350

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Endonuclease G / ENDOG Antibody (clone OTI5F1) LS-C340604

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (OTI5F1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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Endonuclease G / ENDOG Antibody (clone OTI5F1, Carrier-free) LS-C786799

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (Carrier-free) (OTI5F1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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IHC-plus™ Endonuclease G / ENDOG Antibody (clone 7F2G10) LS-B14748

(4.0) Rating

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (7F2G10) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Endonuclease G / ENDOG Antibody (C-Terminus) LS-C111361

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

Endonuclease G / ENDOG Antibody LS-C751672

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

Endonuclease G / ENDOG Antibody (clone 7G1C10) LS-C53491

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (7G1C10) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$502

Select

Endonuclease G / ENDOG Antibody (clone 7G1G10) LS-C53492

Antibody:

Endonuclease G / ENDOG Mouse anti-Human Monoclonal (7G1G10) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$502

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Endonuclease G / ENDOG Antibody (aa188-217) LS-C99302

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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Endonuclease G / ENDOG Antibody LS-C781497

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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Endonuclease G / ENDOG Antibody LS-C498799

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Endonuclease G / ENDOG Antibody (HRP) LS-C498780

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP

• Unconjugated
• HRP

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Endonuclease G / ENDOG Antibody (aa61-110) LS-C199844

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa61-110) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Endonuclease G / ENDOG Antibody LS-C807232

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Endonuclease G / ENDOG Antibody (aa188-217, HRP) LS-C545770

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 µl/$952

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Endonuclease G / ENDOG Antibody (aa188-217, Biotin) LS-C525651

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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Endonuclease G / ENDOG Antibody (aa188-217, FITC) LS-C535666

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

Endonuclease G / ENDOG Antibody (aa188-217, APC) LS-C516484

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

Endonuclease G / ENDOG Antibody (aa188-217, PE) LS-C653847

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa188-217) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• HRP
• Biotin
• FITC
• APC
• PE

• HRP
• Biotin
• FITC
• More...
  • APC
  • PE

Select

Endonuclease G / ENDOG Antibody LS-C314098

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

Endonuclease G / ENDOG Antibody (Internal) LS-C352158

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Endonuclease G / ENDOG Antibody (aa16-290) LS-C372969

Antibody:

Endonuclease G / ENDOG Rabbit anti-Human Polyclonal (aa16-290) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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