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EMD / Emerin

emerin

Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

Gene Name: emerin
Synonyms: EMD, EDMD, Emerin, LEM domain containing 5, LEMD5, STA
Target Sequences: NM_000117 NP_000108.1 P50402

☰ Filters
Antibodies (37)
Proteins (5)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (37)
Recombinant (3)
Sandwich (1)
EMD / Emerin (43)
Human (37)
Mouse (10)
Rat (7)
Chimpanzee (3)
Guinea pig (3)
Rabbit (4)
Rodent (1)
IHC (9)
IHC-Fr (1)
IHC-P (8)
WB (30)
Flo (6)
ELISA (10)
ICC (4)
IF (9)
IP (2)
Peptide-ELISA (1)
rabbit (25)
mouse (11)
sheep (1)
Product Group
IHCPlus (1)
IgG (17)
IgG1 (6)
IgG1,k (2)
IgG2a,k (1)
IgG2b,k (2)
monoclonal mc (12)
polyclonal pc (25)
11C1029 (1)
3B9 (1)
8F5A8 (1)
8F5G2 (1)
EMD/2167 (2)
EMD/2168 (2)
MANEM1(5D10) (1)
96-Well Strip Plate (1)
Azide-free (2)
Biotin Conjugated (2)
BSA-free (2)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (29)
aa34-83 (4)
N-Terminus (2)
Leu12 (1)
aa1-50 (1)
aa187-213 (1)
No (43)
Plasma (1)
Serum (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
EMD / Emerin Antibody - Anti-EMD / Emerin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
EMD / Emerin Antibody - Immunofluorescence of monoclonal antibody to EMD on HeLa cell. [antibody concentration 10 ug/ml]
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EMD / Emerin Mouse anti-Human Monoclonal (3B9) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
EMD / Emerin Antibody - EMD / Emerin antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EMD / Emerin Rabbit anti-Human Polyclonal (aa34-83) (Biotin) Antibody
Rabbit, Guinea pig, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
EMD / Emerin Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using EMD Antibody at dilution of 1:100
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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EMD / Emerin Rabbit anti-Human Monoclonal (N-Terminus) (11C1029) Antibody
Human
IP, WB
Unconjugated
100 µl/$688
Select
EMD / Emerin Mouse anti-Human Monoclonal (8F5A8) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
EMD / Emerin Antibody - IHC analysis of Emerin using anti-Emerin antibody. Emerin was detected in paraffin-embedded section of human gastric cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-Emerin Antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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EMD / Emerin Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
EMD / Emerin Antibody - Immunohistochemistry of paraffin-embedded human thyroid cancer using EMD antibody at dilution of 1:200 (400x lens).
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
EMD / Emerin Antibody - IHC analysis of Emerin using anti-Emerin antibody. Emerin was detected in paraffin-embedded section of human endometrial carcinoma tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml rabbit anti-Emerin Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
EMD / Emerin Antibody - Normal human fibroblast cells stained with MANNES1A(7A12) + DAPI
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EMD / Emerin Mouse anti-Human Monoclonal (MANEM1(5D10)) Antibody
Rabbit, Human
ICC, IF, WB
Unconjugated
0.1 mg/$482
EMD / Emerin Antibody - Immunofluorescent analysis of Emerin staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
EMD / Emerin Antibody - IHC testing of FFPE human breast carcinoma with Emerin antibody (clone EMD/2167). Required HIER: boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to staining.
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EMD / Emerin Mouse anti-Human Monoclonal (EMD/2167) Antibody
Human
IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
EMD / Emerin Antibody - IHC testing of FFPE human breast carcinoma with Emerin antibody (clone EMD/2167). Required HIER: boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to staining.
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EMD / Emerin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (EMD/2167) Antibody
Human
IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
EMD / Emerin Antibody - IHC testing of FFPE human basal cell carcinoma with Emerin antibody (clone EMD/2168). Required HIER: boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to staining.
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EMD / Emerin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (EMD/2168) Antibody
Human
IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
EMD / Emerin Antibody - IHC testing of FFPE human basal cell carcinoma with Emerin antibody (clone EMD/2168). Required HIER: boiling tissue sections in 10mM citrate buffer, pH 6, for 10-20 min and allow to cool prior to staining.
Select
EMD / Emerin Mouse anti-Human Monoclonal (EMD/2168) Antibody
Human
IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
EMD / Emerin Antibody - Immunocytochemistry/ Immunofluorescence - Anti-Emerin antibody at a 1/100 dilution
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EMD / Emerin Sheep anti-Rodent Polyclonal (N-Terminus) Antibody
Rodent
ICC, IF, WB
Unconjugated
50 µl/$482
EMD / Emerin Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer using EMD antibody at dilution of 1:100 (40x lens).
Select
EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
EMD / Emerin Mouse anti-Human Monoclonal (8F5G2) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
EMD / Emerin Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
EMD / Emerin Antibody - Western blot of EMD pAb in extracts from Hela, Jurkat, PC3, U251 and Y79 cells.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
EMD / Emerin Antibody - Western blot of EMD antibody in MCF-7 cell line lysates (35 ug/lane). EMD (arrow) was detected using the purified antibody.
Select
EMD / Emerin Rabbit anti-Human Polyclonal (aa187-213) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
EMD / Emerin Antibody - IHC testing of FFPE human intestinal cancer tissue with Emerin antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
Select
EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
EMD / Emerin Antibody - Western blot analysis of 293T and MCF-7 cell, human hepatocellular carcinoma tissue and Raji cell, A431 and A549 cell, using EMD Polyclonal Antibody at dilution of 1:1200.
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EMD / Emerin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 43 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).