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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498776-50 | 50 µg | $294 |
| LS-C498776-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human EMD / Emerin Antibody (IHC, IF, WB) LS‑C498776
Polyclonal Rabbit anti‑Human EMD / Emerin Antibody (IHC, IF, WB) LS‑C498776
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
Emerin antibody LS-C498776 is an unconjugated rabbit polyclonal antibody to Emerin (EMD) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Target
Human EMD / Emerin
Synonyms
EMD | EDMD | Emerin | LEM domain containing 5 | LEMD5 | STA
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Emerin protein (1-222AA)
Specificity
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About EMD / Emerin
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Featured Products
![EMD / Emerin Antibody - Immunofluorescence of monoclonal antibody to EMD on HeLa cell. [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com//image2/emd-emerin-antibody-clone-3b9-ls-c133167/50640_622265.jpg)
Species:
Human
Applications:
Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Chimpanzee, Guinea pig, Rabbit
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
