Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone GP1.4] (IgG1) to Human EMA / MUC1
IHC, IHC - Paraffin
Mouse Monoclonal [clone VU-2G7] (IgG1) to Human EMA / MUC1
IHC, IHC - Paraffin, IHC - Frozen, ELISA
Human EMA / MUC1
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [VU-2G7]
IHC - Paraffin
IHC - Frozen
Specificity and Use
EMA / MUC1 antibody was raised against synthetically glycosylated MUC1 60mer tandem repeat NH2-(HGVTSAPDT(GalNAc)RPAPGSTAPPAHG)3-COOH, conjugated to BSA. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%).
Recognizes MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia.
Suitable for use in ELISA and Immunohistochemistry: frozen, paraffin.
PBS, 0.05% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
EMA / MUC1 is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas.