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| Catalog Number | Size | Price |
|---|---|---|
| LS-C202434-100 | 100 µg (100 µg/ml) | $432 |
Monoclonal Mouse anti‑Human EMA / MUC1 Antibody (clone VU‑11D1, Concentrated, IHC) LS‑C202434
Monoclonal Mouse anti‑Human EMA / MUC1 Antibody (clone VU‑11D1, Concentrated, IHC) LS‑C202434
Antibody:
EMA / MUC1 Mouse anti-Human Monoclonal (Concentrated) (VU-11D1) Antibody
Application:
IHC, IHC-P, IHC-Fr, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
EMA / MUC1 Mouse anti-Human Monoclonal (Concentrated) (VU-11D1) Antibody
Application:
IHC, IHC-P, IHC-Fr, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Specifications
Description
MUC1 antibody LS-C202434 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for ELISA and IHC.
Target
Human EMA / MUC1
Synonyms
MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
VU-11D1
Conjugations
Unconjugated
Purification
Purified
Modifications
Concentrated
Immunogen
Live cells (107 cells/dose in PBS) of human breast cancer cell line ZR-75-1. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability of the hybridomas was established by subcloning four times.
Specificity
VU-11D1 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. The dominant epitope of mAb VU11D1 is the 7-mer TSAPDTR of the MUC1 tandem repeat as established with epitope fingerprinting.
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.05% Sodium Azide
Storage
Store at 2-8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About EMA / MUC1
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Flow Cytometry
Species:
Human, Mouse, Pig
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/15/2024
Date Requested: 4/15/2024
