ELL3

Elongation Factor RNA Polymerase II-like 3

Enhancer-binding elongation factor that specifically binds enhancers in embryonic stem cells (ES cells), marks them, and is required for their future activation during stem cell specification. Does not only bind to enhancer regions of active genes, but also marks the enhancers that are in a poised or inactive state in ES cells and is required for establishing proper RNA polymerase II occupancy at developmentally regulated genes in a cohesin-dependent manner. Probably required for priming developmentally regulated genes for later recruitment of the super elongation complex (SEC), for transcriptional activation during differentiation. Required for recruitment of P-TEFb within SEC during differentiation. Probably preloaded on germ cell chromatin, suggesting that it may prime gene activation by marking enhancers as early as in the germ cells. Promoting epithelial-mesenchymal transition (EMT) By similarity. Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968).

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Products

Antibodies (13)

Proteins (2)

Type

Primary (13)

Recombinant (2)

Target

ELL3 (15)

Reactivity

Human (12)

Mouse (5)

Application

WB (13)

ELISA (7)

Host

rabbit (12)

mouse (1)

Isotype

IgG (7)

Clonality

polyclonal pc (13)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa334-360 (7)

C-Terminus (4)

Publications

No (15)

Tag

GST (1)

His, N-Terminal (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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ELL3 Antibody (C-Terminus) LS-C170371

Antibody:

ELL3 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ELL3 Antibody (C-Terminus, HRP) LS-C469998

Antibody:

ELL3 Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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ELL3 Antibody (C-Terminus, Biotin) LS-C469939

Antibody:

ELL3 Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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ELL3 Antibody (C-Terminus, FITC) LS-C469940

Antibody:

ELL3 Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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ELL3 Antibody (aa334-360) LS-C159522

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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ELL3 Antibody (aa334-360) LS-C321089

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ELL3 Antibody (aa334-360, Biotin) LS-C208875

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ELL3 Antibody (aa334-360, FITC) LS-C208876

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

ELL3 Antibody (aa334-360, APC) LS-C208874

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ELL3 Antibody (aa334-360, Azide-free, HRP) LS-C208877

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ELL3 Antibody (aa334-360, PE) LS-C208878

Antibody:

ELL3 Rabbit anti-Human Polyclonal (aa334-360) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ELL3 Antibody LS-C780385

Antibody:

ELL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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ELL3 Antibody LS-C307387

Antibody:

ELL3 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Select

Human ELL3 Protein (Recombinant GST) (Full Length) - LS-G35406

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.41 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human ELL3 Protein (Recombinant His, N-Terminal) - LS-G144675

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

45.2 kDa

Price:

50 µg/$419

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