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ELAVL1 / HUR

ELAV like RNA binding protein 1

RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA.

Gene Name: ELAV like RNA binding protein 1
Synonyms: ELAVL1, ELAV1, Hua, HUR, Hu antigen R, ELAV-like protein 1, Hu-antigen R, MelG
Target Sequences: NM_001419 NP_001410.2 Q15717

Publications (1)

1
miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR. Balkhi MY, Iwenofu OH, Bakkar N, Ladner KJ, Chandler DS, Houghton PJ, London CA, Kraybill W, Perrotti D, Croce CM, Keller C, Guttridge DC. Science signaling. 2013 6:ra63. (WB; Human) [Full Text Article] [PubMed:23901138] Related Antibodies: LS-B4316.

☰ Filters
Antibodies (50)
Proteins (7)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (50)
Recombinant (5)
Sandwich (2)
ELAVL1 / HUR (59)
Human (51)
Mouse (18)
Rat (13)
Bat (1)
Bovine (2)
Chicken (1)
Dog (1)
Horse (1)
Monkey (1)
Pig (2)
Rabbit (1)
Sheep (2)
IHC (19)
IHC-P (5)
WB (49)
Flo (1)
ELISA (21)
ICC (5)
IF (20)
IP (4)
Peptide-ELISA (1)
rabbit (32)
mouse (18)
Product Group
IHCPlus (2)
IgG (26)
IgG1 (4)
IgG1,k (14)
monoclonal mc (18)
polyclonal pc (32)
224CT6.5.3 (6)
4G8 (1)
OTI14F11 (2)
OTI14F4 (2)
96-Well Strip Plate (2)
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Azide-free (1)
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aa1-13 (1)
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Yes (1)
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6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (2)
ELAVL1 / HUR Antibody - Anti-HuR antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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ELAVL1 / HUR Mouse anti-Human Monoclonal (4G8) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ELAVL1 / HUR Antibody - Anti-HuR antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ELAVL1 / HUR Rabbit anti-Human Polyclonal (aa1-13) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
ELAVL1 / HUR Protein
Select
E. coli
6His, N-terminus
31 kDa
10 µg/$265; 50 µg/$315
ELAVL1 / HUR Protein
Select
HEK 293 Cells
His, N-Terminal
40 kDa-27 kDa
10 µg/$289; 200 µg/$646; 50 µg/$360
ELAVL1 / HUR Antibody - Immunohistochemistry of paraffin-embedded human prostate.
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
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ELAVL1 / HUR Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
1 ml/$842
ELAVL1 / HUR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$893
ELAVL1 / HUR Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using ELAVL1 Polyclonal Antibody at dilution of 1:40.
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ELAVL1 / HUR Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using ELAVL1 Polyclonal Antibody at dilution of 1:50.
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ELAVL1 / HUR Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
ELAVL1 / HUR Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ELAVL1 / HUR Antibody - Immunohistochemistry of paraffin-embedded human prostate using ELAVL1 antibody at dilution of 1:100 (40x lens).
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
ELAVL1 / HUR Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ELAVL1 mouse monoclonal antibody. (Dilution 1:50).
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ELAVL1 / HUR Mouse anti-Human Monoclonal (OTI14F4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ELAVL1 / HUR Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ELAVL1 mouse monoclonal antibody. (Dilution 1:50).
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ELAVL1 / HUR Mouse anti-Human Monoclonal (Carrier-free) (OTI14F4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ELAVL1 / HUR Protein - 12.5% SDS-PAGE of human ELAVL1 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.5 kDa
2 µg/$439
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ELAVL1 / HUR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (224CT6.5.3) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (Biotin) (224CT6.5.3) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (FITC) (224CT6.5.3) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
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ELAVL1 / HUR Mouse anti-Human Monoclonal (APC) (224CT6.5.3) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (Azide-free) (HRP) (224CT6.5.3) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (PE) (224CT6.5.3) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$904
Select
ELAVL1 / HUR Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$904
Viewing 1-25 of 59 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).