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ELAC2

elaC ribonuclease Z 2

ELAC2 has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: elaC ribonuclease Z 2
Synonyms: ELAC2, ElaC (E. coli) homolog 2, ElaC homolog 2 (E. coli), ELC2, ElaC homolog protein 2, HPC2, RNase Z 2, Ribonuclease Z 2, TRNA 3 endonuclease 2, TRNase Z (long form), TRNase Z 2
Target Sequences: NM_018127 NP_060597.4 Q9BQ52

☰ Filters
Antibodies (27)
Proteins (5)
Over-Expression Lysate (2)
Primary (27)
Recombinant (3)
ELAC2 (32)
Human (27)
Mouse (2)
Rat (1)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (3)
IHC (9)
IHC-P (1)
WB (18)
ELISA (9)
ICC (1)
IF (9)
IP (3)
Peptide-ELISA (2)
rabbit (20)
mouse (7)
Product Group
IHCPlus (1)
IgG (17)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (21)
APC Conjugated (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (14)
aa345-394 (4)
130-210 aa, Internal (1)
aa150-200 (1)
aa161-210 (1)
aa2-101 (1)
aa776-826 (1)
No (32)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
ELAC2 Antibody - Immunofluorescence staining of ELAC2 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human ELAC2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IP, WB
Unconjugated
100 µl/$412
ELAC2 Antibody - Anti-ELAC2 antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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ELAC2 Rabbit anti-Human Polyclonal (aa161-210) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
ELAC2 Antibody - Immunohistochemistry of paraffin-embedded human esophagus.
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ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ELAC2 Antibody - Detection of mouse ELAC2 by immunohistochemistry. Sample: FFPE section of mouse plasmacytoma. Antibody: Affinity purified rabbit anti- ELAC2 used at a dilution of 1:1,000 (1µg/ml). Detection: DAB
Select
ELAC2 Rabbit anti-Human Polyclonal (aa150-200) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ELAC2 Antibody - Detection of mouse ELAC2 by immunohistochemistry. Sample: FFPE section of mouse plasmacytoma. Antibody: Affinity purified rabbit anti- ELAC2 used at a dilution of 1:1,000 (1µg/ml). Detection: DAB
Select
ELAC2 Rabbit anti-Human Polyclonal (aa776-826) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
ELAC2 Mouse anti-Human Monoclonal (aa2-101) Antibody
Human
ELISA, IF
Unconjugated
100 µg/$705
Select
ELAC2 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µl/$904
Select
ELAC2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF
Biotin Conjugated
100 µl/$904
Select
ELAC2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF
FITC Conjugated
100 µl/$904
Select
ELAC2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF
PE Conjugated
100 µl/$904
Select
ELAC2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF
APC Conjugated
100 µl/$904
ELAC2 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ELAC2 Rabbit anti-Human Polyclonal (130-210 aa, Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ELAC2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ELAC2 antibody.
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
Select
ELAC2 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
Select
ELAC2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
ELAC2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
ELAC2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
ELAC2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
ELAC2 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
ELAC2 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
ELAC2 Antibody - Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ELAC2 Rabbit anti-Human Polyclonal (aa345-394) Antibody
Human
WB
Unconjugated
100 µl/$424
ELAC2 Antibody - Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ELAC2 Rabbit anti-Human Polyclonal (aa345-394) (HRP) Antibody
Dog, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
Viewing 1-25 of 32 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).