Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
ELAC2 antibody was raised against synthetic peptide located between aa345-394 of human ELAC2 (Q9BQ52-2). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Dog (100%); Orangutan (92%); Gorilla (85%); Mouse (83%).
Human ELAC2 / HPC2
Lyophilized from PBS, 2% sucrose.
50 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
ELAC2 Antibody, ElaC (E. coli) homolog 2 Antibody, ElaC homolog 2 (E. coli) Antibody, ELC2 Antibody, ElaC homolog protein 2 Antibody, HPC2 Antibody, RNase Z 2 Antibody, Ribonuclease Z 2 Antibody, TRNA 3 endonuclease 2 Antibody, TRNase Z (long form) Antibody, TRNase Z 2 Antibody
ELAC2 has a C-terminal domain with tRNA 3&#8242; processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer.