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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ELAC2 Antibody (aa345‑394) LS‑C201394
ELAC2 antibody LS-C201394 is an unconjugated rabbit polyclonal antibody to ELAC2 from human, dog and monkey. Validated for WB.
Catalog
Size
Price
LS-C201394-50
50 µg (1 mg/ml)
Unavailable

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Product Description

ELAC2 antibody LS-C201394 is an unconjugated rabbit polyclonal antibody to ELAC2 from human, dog and monkey. Validated for WB.
About ELAC2
ELAC2 has a C-terminal domain with tRNA 3' processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Q9BQ52 NM_018127 NP_060597.4

ELAC2 Antibody, ElaC (E. coli) homolog 2 Antibody, ElaC homolog 2 (E. coli) Antibody, ELC2 Antibody, ElaC homolog protein 2 Antibody, HPC2 Antibody, RNase Z 2 Antibody, Ribonuclease Z 2 Antibody, TRNA 3 endonuclease 2 Antibody, TRNase Z (long form) Antibody, TRNase Z 2 Antibody


Specifications

Target
Human ELAC2
Host
Rabbit
Reactivity
Human, Monkey, Dog (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
ELAC2 antibody was raised against synthetic peptide located between aa345-394 of human ELAC2 (Q9BQ52-2). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Dog (100%); Orangutan (92%); Gorilla (85%); Mouse (83%).
Epitope
aa345-394
Specificity
Human ELAC2 / HPC2
Presentation
Lyophilized from PBS, 2% sucrose.
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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