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EIF4E

eukaryotic translation initiation factor 4E

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

Gene Name: eukaryotic translation initiation factor 4E
Synonyms: EIF4E, EIF-4E, EIF4E1, EIF4EL1, EIF4F, CBP, EIF-4F 25 kDa subunit, MRNA cap-binding protein
Target Sequences: NM_001968 NP_001959.1 P06730

Publications (2)

1
Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells. Peruquetti RL, de Mateo S, Sassone-Corsi P. PloS one. 2012 7:e42695. [PubMed:22900038] [PMC:PMC3416844]
2
Licochalcone A inhibits EGFR signalling and translationally suppresses survivin expression in human cancer cells. Feng Gao, Ming Li, Xinfang Yu, Wenbin Liu, Li Zhou, Wei Li. Journal of cellular and molecular medicine. 2020 November; [Full Text Article] [PubMed:33247550] [PMC:PMC7812290] Related Antibodies: LS-B12932.

☰ Filters
Antibodies (86)
Proteins (7)
Over-Expression Lysate (2)
Primary (86)
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EIF4E (93)
Human (84)
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rabbit (65)
mouse (21)
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monoclonal mc (20)
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1504CT774.14.55 (1)
163CT48.1.9 (6)
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Low endotoxin level (2)
EIF4E Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EIF4E Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
EIF4E Antibody - Anti-EIF4E antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EIF4E Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
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E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
25.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
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EIF4E Rabbit anti-Human Polyclonal (pSer209) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$717
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EIF4E Mouse anti-Human Monoclonal (Biotin) (163CT48.1.9) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
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EIF4E Mouse anti-Human Monoclonal (APC) (163CT48.1.9) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
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EIF4E Mouse anti-Human Monoclonal (Azide-free) (HRP) (163CT48.1.9) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
EIF4E Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-EIF4E mouse monoclonal antibody.
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EIF4E Mouse anti-Human Monoclonal (OTI5D11) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
EIF4E Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF4E (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF4E.
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EIF4E Mouse anti-Human Monoclonal (OTI6C11) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
EIF4E Antibody - IHC of paraffin-embedded liver cancer (left) and submaxillary tumor (right) using EIF4E mouse monoclonal antibody with DAB staining.
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EIF4E Mouse anti-Human Monoclonal (5D11) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
EIF4E Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded liver cancer (left) and submaxillary tumor (right) with DAB staining using eIF4E Monoclonal Antibody.
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EIF4E Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
EIF4E Antibody - eIF4E Antibody in Immunofluorescence (IF)
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EIF4E Mouse anti-Human Monoclonal (5D11) Antibody
Mouse, Human
ICC, IF, IP, WB
Unconjugated
100 µg/$541
EIF4E Antibody - Anti-EIF4E antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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EIF4E Rabbit anti-Human Polyclonal (aa168-217) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
EIF4E Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue.
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EIF4E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
EIF4E Antibody - 1:200 staining human colon carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EIF4E Rabbit anti-Human Polyclonal (pSer209) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) Antibody
Flo, ICC, IHC, IP, WB
Unconjugated
200 µl/$734
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) (Biotin) Antibody
Human
ELISA, Flo, ICC, IHC, IP, WB
Biotin Conjugated
200 µl/$952
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) (FITC) Antibody
Human
ELISA, Flo, ICC, IHC, IP, WB
FITC Conjugated
200 µl/$952
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) (APC) Antibody
Human
ELISA, Flo, ICC, IHC, IP, WB
APC Conjugated
200 µl/$952
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) (PE) Antibody
Human
ELISA, Flo, ICC, IHC, IP, WB
PE Conjugated
200 µl/$952
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EIF4E Rabbit anti-Human Polyclonal (aa32-61) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IHC, IP, WB
HRP Conjugated, Azide-free
200 µl/$952
EIF4E Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EIF4E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EIF4E Antibody - Formalin-fixed and paraffin-embedded human testis tissue reacted with EIF4E Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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EIF4E Rabbit anti-Human Polyclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
EIF4E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
EIF4E Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Viewing 1-25 of 93 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).