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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EIF2AK2 / PKR Antibody (Lys440) LS‑C177696
PKR antibody LS-C177696 is an unconjugated rabbit polyclonal antibody to human PKR (EIF2AK2). Validated for IHC and WB.
Catalog
Size
Price
LS-C177696-100
100 µl
Unavailable

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Product Description

PKR antibody LS-C177696 is an unconjugated rabbit polyclonal antibody to human PKR (EIF2AK2). Validated for IHC and WB.
About EIF2AK2 / PKR
IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV-1). P19525 NM_002759 NP_002750.1

EIF2AK2 Antibody, p1/eIF-2A protein kinase Antibody, p68 kinase Antibody, PRKR Antibody, EIF-2A protein kinase 2 Antibody, p68 Antibody, Protein kinase RNA-activated Antibody, Tik Antibody


Specifications

Target
Human EIF2AK2 / PKR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
EIF2AK2 / PKR antibody was raised against synthetic peptide around Lys440 of human EIF2AK2
Epitope
Lys440
Specificity
Human EIF2AK2
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of PKR (K440) pAb in extracts from K562 cells.
Western blot of PKR (K440) pAb in extracts from K562 cells.

Immunohistochemistry

IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of PKR (K440) pAb in extracts from K562 cells.
Western blot of PKR (K440) pAb in extracts from K562 cells.

Immunohistochemistry

IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of PKR (K440) pAb in extracts from K562 cells.
Western blot of PKR (K440) pAb in extracts from K562 cells.

Immunohistochemistry

IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of PKR (K440) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of PKR (K440) pAb in extracts from K562 cells.
Western blot of PKR (K440) pAb in extracts from K562 cells.


Requested From: 
Date Requested: 6/25/2018

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