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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EIF2AK1 Antibody (aa1‑138) LS‑C152793
EIF2AK1 antibody LS-C152793 is an unconjugated rabbit polyclonal antibody to EIF2AK1 from human, mouse and rabbit. Validated for IP and WB.
Catalog
Size
Price
LS-C152793-100
100 µl
Unavailable

Popular EIF2AK1 Products

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with EIF2AK1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-EIF2AK1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4656 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Western blot of HRI antibody
Species: Human, Monkey, Mouse
Applications: IHC, Western blot, ELISA
Immunohistochemistry of paraffin-embedded human testis tissue at dilution of 1:100
Species: Human
Applications: IHC, Immunofluorescence, Western blot, ELISA

Product Description

EIF2AK1 antibody LS-C152793 is an unconjugated rabbit polyclonal antibody to EIF2AK1 from human, mouse and rabbit. Validated for IP and WB.
About EIF2AK1
Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser-48' and 'Ser-51', thus preventing its recycling. Binds hemin forming a 1:1 complex through a cysteine thiolate and histidine nitrogenous coordination. Q9BQI3 NM_014413 NP_055228.2

EIF2AK1 Antibody, Heme-regulated repressor Antibody, HRI Antibody, KIAA1369 Antibody, HCR Antibody, Heme-controlled repressor Antibody, Heme-regulated inhibitor Antibody


Specifications

Target
Mouse EIF2AK1
Host
Rabbit
Reactivity
Mouse, Human, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
Immunogen
EIF2AK1 antibody was raised against 6His-tagged fusion protein corres-ponding to residues 1-138 of mouse heme-regulated inhibitor (HRI)
Epitope
aa1-138
Specificity
HRI
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).
WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).

Western blot

WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).
WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).

Western blot

WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).
WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).

Western blot

WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).
WB: Mouse reticulocyte lysate was probed with anti-HRI (1:5000 dilution).


Requested From: 
Date Requested: 6/19/2018

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