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EHMT2 / G9A

euchromatic histone-lysine N-methyltransferase 2

Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Gene Name: euchromatic histone-lysine N-methyltransferase 2
Synonyms: EHMT2, BAT8, C6orf30, Em:AF134726.3, KMT1C, G9A, GAT8, H3-K9-HMTase 3, Protein G9a, G9A histone methyltransferase, HLA-B associated transcript 8, HLA-B-associated transcript 8, Lysine N-methyltransferase 1C, NG36
Target Sequences: NM_006709 NP_006700.3 Q96KQ7

☰ Filters
Antibodies (32)
Proteins (5)
Over-Expression Lysate (4)
Primary (32)
Recombinant (1)
EHMT2 / G9A (37)
Human (31)
Mouse (13)
Rat (4)
Chimpanzee (3)
Dog (3)
Monkey (4)
Rabbit (3)
IHC (6)
WB (31)
Flo (9)
ELISA (10)
ICC (1)
IF (1)
IP (1)
Peptide-ELISA (4)
rabbit (30)
mouse (2)
IgG (19)
IgG1 (2)
monoclonal mc (3)
polyclonal pc (29)
2D12A11 (1)
6F3E5 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (19)
aa159-186 (7)
aa144-193 (4)
aa1160-C-term (2)
C-Terminus (1)
aa227-259 (1)
aa361-395 (1)
aa589-623 (1)
aa71-88 (1)
No (37)
Myc-DDK (Flag) (5)
Human (3)
293T Cells (2)
HEK 293 Cells (3)
Select
EHMT2 / G9A Rabbit anti-Human Monoclonal (C-Terminus) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$688
EHMT2 / G9A Antibody - Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using EHMT2 mouse mAb with DAB staining.
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EHMT2 / G9A Mouse anti-Human Monoclonal (2D12A11) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µg/$459
EHMT2 / G9A Antibody - Western blot of EHMT2 pAb in extracts from Jurkat, HEK-293 and Hela cells.
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EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
EHMT2 / G9A Antibody - EHMT2 / G9A antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EHMT2 / G9A Rabbit anti-Human Polyclonal (aa144-193) Antibody
Human
WB
Unconjugated
100 µl/$424
EHMT2 / G9A Antibody - Western blot analysis using EHMT2 mAb against HEK293 (1) and EHMT2 (AA: 317-471)-hIgGFc transfected HEK293 (2) cell lysate.
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EHMT2 / G9A Mouse anti-Human Monoclonal (6F3E5) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
EHMT2 / G9A Protein - Purified recombinant protein EHMT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
128.8 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
128.8 kDa
20 µg/$215
EHMT2 / G9A Antibody - Detection of Human G9A/EHMT2 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-G9A/EHMT2 used at a dilution of 1:1000 (1 Detection: DAB.
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EHMT2 / G9A Rabbit anti-Human Polyclonal (aa1160-C-term) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
EHMT2 / G9A Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EHMT2 / G9A Antibody - Western blot analysis of extracts of Mouse spleen tissue.
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EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
EHMT2 / G9A Antibody - EHMT2 Antibody western blot of Jurkat cell line lysates (15 ug/lane). The EHMT2 antibody detected the EHMT2 protein (arrow).
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EHMT2 / G9A Rabbit anti-Human Polyclonal (aa159-186) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
EHMT2 / G9A Rabbit anti-Mouse Polyclonal (aa227-259) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
EHMT2 / G9A Antibody - Anti-Ehmt2 Antibody at 1:1000 dilution + mouse brain lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 138 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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EHMT2 / G9A Rabbit anti-Mouse Polyclonal (aa589-623) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
400 µl/$393
EHMT2 / G9A Antibody - Western blot of lysates from HeLa, Jurkat, A431, mouse NIH/3T3 cell line (from left to right), using EHMT2 antibody diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa361-395) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
EHMT2 / G9A Antibody - Detection of Human G9A/EHMT2 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-G9A/EHMT2 used at a dilution of 1:100. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa1160-C-term) Antibody
Human
IHC
Unconjugated
1 µg/$295; 100 µl/$532
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal (aa71-88) Antibody
Human, Monkey
WB
Unconjugated
200 µg/$947
Select
EHMT2 / G9A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$680
Viewing 1-25 of 37 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).