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Anti-EGLN3 / PHD3 Antibody (aa95-108) LS-C3376

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $265
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Rabbit Polyclonal to Human EGLN3 / PHD3
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig
ELISA
Unconjugated

Details

Human EGLN3 / PHD3
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Polyclonal
Protein G purified

Applications

ELISA (1:1000)

Specificity and Use

EGLN3 / PHD3 antibody was raised against synthetic peptide from human EGLN3 / PHD3. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Pig (100%); Opossum (93%); Chicken (86%).
aa95-108
KLH conjugated synthetic peptide comprising amino acids 95 - 108 [MPLGHIMRLDLEKI] of the human egl nine homolog 3 (EGLN3) protein.

Packaging

PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About EGLN3 / PHD3

Q9H6Z9 NM_022073 NP_071356.1

EGLN3 Antibody, HPH-1 Antibody, HIF prolyl hydroxylase 3 Antibody, HIF-prolyl hydroxylase 3 Antibody, HIFPH3 Antibody, PHD3 Antibody, EGL nine (C.elegans) homolog 3 Antibody, Egl nine homolog 3 Antibody, HIF-PH3 Antibody, HIFP4H3 Antibody

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site.

Requested From: United States
Date Requested: 9/29/2016

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