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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EGLN2 / PHD1 Antibody (aa160‑177) LS‑C3265
PHD1 antibody LS-C3265 is an unconjugated rabbit polyclonal antibody to human PHD1 (EGLN2). Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C3265-100
100 µg
Unavailable

Popular EGLN2 / PHD1 Products

Anti-EGLN2 / PHD1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1524 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Western blot of human PHD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with EGLN2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

PHD1 antibody LS-C3265 is an unconjugated rabbit polyclonal antibody to human PHD1 (EGLN2). Validated for ELISA.
About EGLN2 / PHD1
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Q96KS0 NM_017555 NP_444274.1

EGLN2 Antibody, EIT6 Antibody, EGL nine (C.elegans) homolog 2 Antibody, Egl nine homolog 2 Antibody, HPH-1 Antibody, HPH-3 Antibody, Estrogen-induced tag 6 Antibody, PHD1 Antibody, HIF-PH1 Antibody, HIF-prolyl hydroxylase 1 Antibody, HIFPH1 Antibody


Specifications

Target
Human EGLN2 / PHD1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA (1:1000)
Immunogen
EGLN2 / PHD1 antibody was raised against synthetic peptide from human EGLN2 / PHD1. Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey (100%); Gorilla, Marmoset, Elephant (94%); Bovine (83%).
Epitope
aa160-177
Specificity
KLH conjugated synthetic peptide comprising amino acids 160 - 177 [EASAGLMEEALPSAPERL] of the human egl nine homolog 2 (EGLN2) protein.
Presentation
PBS, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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