EFNA1 / Ephrin A1

ephrin-A1

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

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Products

Antibodies (44)

Proteins (20)

ELISA Kits (17)

Type

Custom (4)

Over-Expression Lysate (4)

Primary (44)

Recombinant (16)

Sandwich (12)

Sandwich CLIA (1)

Target

EFNA1 / Ephrin A1 (81)

Reactivity

Human (43)

Mouse (27)

Rat (14)

Chicken (1)

Dog (1)

Monkey (1)

Pig (2)

Porcine (1)

Rabbit (2)

Sheep (1)

Application

IHC (16)

IHC-P (5)

WB (32)

ELISA (17)

IF (4)

IP (6)

Peptide-ELISA (2)

Host

rabbit (42)

mouse (1)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (25)

Clonality

monoclonal mc (2)

polyclonal pc (42)

Clone

067 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (15)

APC (1)

APC Conjugated (3)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Preservative Free (2)

Unconjugated (24)

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Epitope

aa19-182 (9)

40-120 aa, Internal (1)

C-Terminus (1)

Internal (1)

aa144-155 (1)

aa66-115 (1)

Publications

No (81)

Sample Type

Cell Lysates (1)

Plasma (8)

Serum (8)

Tissue Homogenates (4)

Tag

6His, C-terminus (2)

Fc, C-terminus (3)

Fc/6His,C-terminus (1)

Fc-6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (3)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (13)

Mouse (3)

Rat (2)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (3)

Human Cells (3)

Mammalian Cells (5)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (8)

Biologically Active

Biologically active (2)

Select

Human EFNA1 / Ephrin A1 (Sandwich ELISA) ELISA Kit - LS-F11356

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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IHC-plus™ EFNA1 / Ephrin A1 Antibody (aa66-115) LS-B9141

(4.0) Rating

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal (aa66-115) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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EFNA1 / Ephrin A1 Antibody (40-120 aa, Internal) LS-C383378

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal (40-120 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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EFNA1 / Ephrin A1 Antibody (Internal) LS-C352138

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rabbit, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

EFNA1 / Ephrin A1 Antibody LS-C335561

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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EFNA1 / Ephrin A1 Antibody (aa19-182) LS-C373221

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal (aa19-182) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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EFNA1 / Ephrin A1 Antibody (clone 067, Preservative Free) LS-C819456

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Rat Monoclonal (Preservative Free) (067) Antibody

Reactivity:

Rat

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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Human EFNA1 / Ephrin A1 (Sandwich ELISA) ELISA Kit - LS-F51822

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

Select

Human EFNA1 / Ephrin A1 (Sandwich ELISA) ELISA Kit - LS-F26847

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Human EFNA1 / Ephrin A1 (Sandwich ELISA) ELISA Kit - LS-F6374

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

Select

EFNA1 / Ephrin A1 Antibody (aa19-182) LS-C375634

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal (aa19-182) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

EFNA1 / Ephrin A1 Antibody (C-Terminus) LS-C6529

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$740

Select

EFNA1 / Ephrin A1 Antibody (HRP) LS-C545810

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$982

Select

EFNA1 / Ephrin A1 Antibody (Biotin) LS-C525691

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$982

Select

EFNA1 / Ephrin A1 Antibody (FITC) LS-C535705

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$982

Select

EFNA1 / Ephrin A1 Antibody (APC) LS-C516515

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

APC Conjugated

Price:

100 µl/$982

Select

EFNA1 / Ephrin A1 Antibody (PE) LS-C653886

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$982

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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EFNA1 / Ephrin A1 Antibody LS-C822639

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

EFNA1 / Ephrin A1 Antibody LS-C486198

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

EFNA1 / Ephrin A1 Antibody LS-C658938

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$386

Select

EFNA1 / Ephrin A1 Antibody LS-C341198

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

EFNA1 / Ephrin A1 Antibody LS-C403979

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

EFNA1 / Ephrin A1 Antibody LS-C400728

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

EFNA1 / Ephrin A1 Antibody LS-C486197

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

EFNA1 / Ephrin A1 Antibody LS-C486202

Antibody:

EFNA1 / Ephrin A1 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

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