Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 236/128] (IgG1) to Edwardsiella tarda
Edwardsiella tarda (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [236/128]
Specificity and Use
Recognizes Edwardsiella tarda. E. tarda is a member of the family Enterobactericeae associated with freshwater ecosystems that that can cause gastoenteritis, wound infections and death due to septicaemia. It is thought that the pathogenicity of this bacteria is due to it's ability to resist phagocytic killing by the host defenses. Replication of E. tarda in murine macrophages is dependant on the type III secretion system and induces an anti-apoptotic effect by up-regulating anti-apoptotic NF-kB target genes.