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EDN1 / Endothelin 1

endothelin 1

EDN1 / Endothelin 1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: endothelin 1
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7
Target Sequences: NM_001955 NP_001946.3 P05305

Publications (2)

1
Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium. Keator CS, Mah K, Ohm L, Slayden OD. Human reproduction (Oxford, England). 2011 26:1715-28. (IHC-Fr; Monkey) [Full Text Article] [PubMed:21505040] [PMC:PMC3113504] Related Antibodies: LS-C11319.
2
B-lymphocyte-intrinsic and -extrinsic defects in secretory immunoglobulin A production in the neural crest-conditional deletion of endothelin receptor B model of Hirschsprung-associated enterocolitis. Giuliana Medrano, Frederic Cailleux, Peihong Guan, Korah Kuruvilla, Amanda J Barlow-Anacker, Ankush Gosain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 June;33:7615-7624. [Full Text Article] [PubMed:30908942] [PMC:PMC6529339]

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Antibodies (104)
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EDN1 / Endothelin 1 (163)
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EDN1 / Endothelin 1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
EDN1 / Endothelin 1 Antibody - Human Placenta, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (aa53-90) Antibody
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$460
EDN1 / Endothelin 1 Antibody - Western Blot analysis of EDN1 expression in transfected 293T cell line by EDN1 monoclonal antibody (M01), clone 3D6.Lane 1: EDN1 transfected lysate(24 KDa).Lane 2: Non-transfected lysate.
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (3D6) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
EDN1 / Endothelin 1 ELISA Kit
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Sandwich
96-Well Microplate
Pig
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
EDN1 / Endothelin 1 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
19 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518; 500 µg/$949
EDN1 / Endothelin 1 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
6.17 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
EDN1 / Endothelin 1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
3.9 - 250 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (C-Terminus) (IC4) Antibody
Human
IHC, IHC-Fr, IRMA
Unconjugated
0.1 mg/$385
EDN1 / Endothelin 1 Antibody - Immunofluorescent detection of mouse GnRH neuronal cells (Rajendren, G and Gibson, MJ 2001 J Neuroendocrinology 13: 270).
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EDN1 / Endothelin 1 Mouse anti-Human Monoclonal (20-2111.41) Antibody
Human
ELISA, IF, IHC, IHC-P, RIA
Unconjugated
100 µg/$548
EDN1 / Endothelin 1 Antibody - EDN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
EDN1 / Endothelin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
EDN1 / Endothelin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.9 - 250 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
EDN1 / Endothelin 1 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
1.25 - 80 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal Antibody
Goat, Sheep, Bovine, Pig, Human
ELISA, IHC, IHC-P, RIA, WB
Unconjugated
20 µl/$488; 100 µl/$953
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa22-38) Antibody
Human
IF, IHC
Unconjugated
50 µl/$572
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa111-138) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
EDN1 / Endothelin 1 Rabbit anti-Human Polyclonal (aa176-203) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Viewing 1-25 of 163 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).