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Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity.
Gene Name: | ER Degradation Enhancer, Mannosidase Alpha-like 3 |
Synonyms: | EDEM3, C1orf22 |
Target Sequences: | NM_025191 NP_079467.3 Q9BZQ6 |
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