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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ECaC / TRPV5 Antibody (aa697‑708) LS‑C55634 Best Seller
TRPV5 antibody LS-C55634 is an unconjugated goat polyclonal antibody to human TRPV5 (ECaC). Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C55634-100
100 µg (0.5 mg/ml)
Unavailable

Popular ECaC / TRPV5 Products

Immunofluorescence analysis of U2OS cells.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: Immunofluorescence, ELISA
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
Biotinylated antibody (2µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP bloc
Species: Human
Applications: ICC, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

TRPV5 antibody LS-C55634 is an unconjugated goat polyclonal antibody to human TRPV5 (ECaC). Validated for Peptide-ELISA and WB.
About ECaC / TRPV5
Constitutively active calcium selective cation channel thought to be involved in Ca2+ reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca2+-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. Q9NQA5 NM_019841 NP_062815.3

TRPV5 Antibody, CAT2 Antibody, Calcium transport protein 2 Antibody, Calcium transporter 2 Antibody, ECAC1 Antibody, Epithelial calcium channel 1 Antibody, ECaC Antibody, OTRPC3 Antibody, Osm-9-like TRP channel 3 Antibody


Specifications

Target
Human ECaC / TRPV5
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Bat, Dog, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:16000) & (1 - 3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Failed Applications
  • IHC - Paraffin
Immunogen
ECaC / TRPV5 antibody was raised against synthetic peptide C-SHRGWEILRQNT from an internal region of human TRPV5 (NP_062815.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bat, Horse, Rabbit (92%); Bovine (83%).
Blocking Peptide
LS-E26703 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55634. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa697-708
Specificity
Human TRPV5.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/21/2018

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