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Anti-EBV LMP2A Antibody (clone 15F9) LS-C57991

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Wt. Vol. Conc. Price
250 µg - - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Related Products

Most Popular EBV LMP2A Antibodies

Anti-EBV LMP2A Antibody (clone 14B7) LS-C57990
Rat Monoclonal [clone 14B7] (IgG2a) to Epstein-Barr Virus EBV LMP2A
Epstein-Barr Virus
Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Anti-EBV LMP2A Antibody (clone 15F9) LS-C57991
Rat Monoclonal [clone 15F9] (IgG1) to Epstein-Barr Virus EBV LMP2A
Epstein-Barr Virus
IHC - Paraffin, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 15F9] (IgG1) to Epstein-Barr Virus EBV LMP2A
Epstein-Barr Virus
IHC - Paraffin, Western blot
Unconjugated

Details

Epstein-Barr Virus EBV LMP2A
Rat
Epstein-Barr Virus (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [15F9]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (1:100 - 1:1000)

Specificity and Use

EBV LMP2A antibody was raised against bacterial TrpE-LMP2A fusion protein.
Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.
Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About EBV LMP2A

Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight viruses in the herpes family, and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis (glandular fever). It is also associated with particular forms of cancer, such as Hodgkin's lymphoma, Burkitt's lymphoma, nasopharyngeal carcinoma, and conditions associated with human immunodeficiency virus (HIV), such as hairy leukoplakia and central nervous system lymphomas.

Requested From: United States
Date Requested: 12/8/2016

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