Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone FE18] (IgG2a) to Ebola Virus
Western blot, ELISA
Ebola Virus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [FE18]
Specificity and Use
Recognizes the Zaire strain of the Ebola virus, a virus that causes hemorrhagic fever. Ebola hemorrhagic fever is potentially lethal and is characterized by a wide range of symptoms including fever, vomiting, diarrhea, generalized pain or malaise, and sometimes internal and external bleeding. The cause of death is usually hypovolemic shock or organ failure. Mortality rates are extremely high, the Zaire strain of the Ebola virus is the most lethal (up to 90% mortality rate). The viruses are characterized by a long, filamentous morphology surrounded by a protein/lipid viral envelope and are transmitted by direct contact with infected blood, body fluids or tissues. Recognizes high molecular weight proteins under non-reducing conditions and a band at approximately 30kD under reducing conditions when used in Western blotting.
Western Blot: LS-C58349 recognizes high molecular weight proteins under non-reducing conditions and a band at approximately 30kD under reducing conditions.