Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
Protein A purified
Western blot (3 - 5 µg/ml)
Specificity and Use
EBI3 / IL-27B antibody was raised against amino acids 51-67 of mouse EBI3 QAPNSTRSTSFIATYRL were used as the immunogen for this antibody. Percent identity with other species by BLAST analysis: Mouse (100%), Elephant (88%), Bovine (82%), Hamster (82%).
PBS, 0.05% BSA, 0.05% sodium azide
Store at 4°C, stable for 6 months. For long term storage, aliquot and store at -20°C.
Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells.