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Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
Gene Name: | early B-cell factor 2 |
Synonyms: | EBF2, Collier, Olf and EBF 2, EBF-2, Early B-cell factor 2, OE-3, O/E-3, COE2, OLF-1/EBF-LIKE 3, Transcription factor COE2 |
Target Sequences: | AK021562 BAB13843.1 Q9HAK2 |
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