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Anti-EAR2 / NR2F6 Antibody (aa21-70) LS-C40527

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular EAR2 / NR2F6 Antibodies

Anti-EAR2 / NR2F6 Antibody (N-Terminus) IHC-plus™ LS-A5745
Rabbit Polyclonal to Human EAR2 / NR2F6
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal (IgG) to Human EAR2 / NR2F6
Human, Mouse, Rat, Bat, Bovine, Dog, Pig
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human EAR2 / NR2F6
Rabbit
Human, Mouse, Rat, Bat, Bovine, Dog, Pig (tested or 100% immunogen sequence identity)
Monkey, Guinea pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

EAR2 / NR2F6 antibody was raised against synthetic peptide located between aa21-70 of human NR2F6 (P10588, NP_005225). Percent identity by BLAST analysis: Human, Chimpanzee, Monkey, Galago, Mouse, Rat, Elephant, Dog, Bovine, Bat, Pig (100%); Marmoset, Guinea pig (92%).
aa21-70
Human NR2F6

Packaging

Lyophilized from PBS with 2% sucrose
50 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

1
Identification of a role for the nuclear receptor EAR-2 in the maintenance of clonogenic status within the leukemia cell hierarchy. Ichim CV, Atkins HL, Iscove NN, Wells RA. Leukemia. 2011 Nov;25:1687-96. [Full Text Article] [PubMed:21637284]

About EAR2 / NR2F6

P10588 NM_005234 AAH02669.3

NR2F6 Antibody, Erba related 2 Antibody, ERBAL2 Antibody, EAR-2 Antibody, EAR2 Antibody, ERBA-related gene-2 Antibody, V-erbA-related protein 2 Antibody

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene.

Western blot

Western blot
A: Marker, HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/9/2016

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