EAR2 / NR2F6

nuclear receptor subfamily 2, group F, member 6

Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).

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Products

Antibodies (45)

ELISA Kits (8)

Proteins (7)

Type

Cell-Based (1)

Over-Expression Lysate (2)

Primary (45)

Recombinant (5)

Sandwich (7)

Target

EAR2 / NR2F6 (60)

Reactivity

Human (48)

Mouse (20)

Rat (21)

Bat (7)

Bovine (9)

Chicken (1)

Chimpanzee (9)

Dog (13)

Guinea pig (4)

Hamster (1)

Monkey (7)

Pig (9)

Porcine (1)

Rabbit (1)

Xenopus (1)

Zebrafish (4)

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Application

IHC (13)

IHC-P (9)

WB (34)

Flo (1)

ELISA (10)

ICC (1)

IF (5)

Peptide-ELISA (3)

Host

rabbit (38)

mouse (6)

goat (1)

Product Group

IHCPlus (2)

PathPlus Cancer (1)

Isotype

IgG (32)

IgG2a (6)

Clonality

monoclonal mc (6)

polyclonal pc (39)

Clone

EM-51 (1)

OTI2C9 (2)

OTI2H4 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (6)

Carrier-free (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (1)

Unconjugated (25)

Epitope

N-Terminus (10)

aa25-53 (7)

aa21-70 (4)

aa264-313 (4)

30-110 aa, N-terminal (1)

Ligand-binding Domain (1)

aa11-60 (1)

aa20-70 (1)

aa394-404 (1)

Publications

No (59)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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EAR2 / NR2F6 Antibody (N-Terminus) LS-C352171

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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EAR2 / NR2F6 Antibody (aa21-70) LS-C40527

(4.0) Rating

(1) Publication(s)

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa21-70) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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EAR2 / NR2F6 Antibody LS-C667251

Antibody:

EAR2 / NR2F6 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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EAR2 / NR2F6 Antibody (aa264-313) LS-C30959

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa264-313) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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EAR2 / NR2F6 Antibody (N-Terminus) LS-B10843

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$485

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EAR2 / NR2F6 Antibody (N-Terminus, HRP) LS-C427551

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

IHC, IHC-P

Format:

HRP Conjugated

Price:

100 µl/$469

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EAR2 / NR2F6 Antibody (N-Terminus, Biotin) LS-C427548

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

IHC, IHC-P

Format:

Biotin Conjugated

Price:

100 µl/$469

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EAR2 / NR2F6 Antibody (N-Terminus, FITC) LS-C427550

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

IHC, IHC-P

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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EAR2 / NR2F6 Antibody LS-C822582

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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EAR2 / NR2F6 Antibody LS-C809225

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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EAR2 / NR2F6 Antibody (aa11-60) LS-C118774

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa11-60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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EAR2 / NR2F6 Antibody (30-110 aa, N-terminal) LS-C383246

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PathPlus™ EAR2 / NR2F6 Antibody (N-Terminus) LS-A5745

Cancer

Fast Shipping

(5.0) Rating

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ EAR2 / NR2F6 Antibody (Ligand-binding Domain) LS-A5701

Fast Shipping

(4.0) Rating

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (Ligand-binding Domain) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Human EAR2 / NR2F6 (Sandwich ELISA) ELISA Kit - LS-F36138

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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EAR2 / NR2F6 Antibody LS-C671356

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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EAR2 / NR2F6 Antibody (clone EM-51) LS-C742173

Antibody:

EAR2 / NR2F6 Mouse anti-Human Monoclonal (EM-51) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

0.1 mg/$337

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EAR2 / NR2F6 Antibody (aa25-53) LS-C323442

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EAR2 / NR2F6 Antibody (aa25-53, Biotin) LS-C264733

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

EAR2 / NR2F6 Antibody (aa25-53, FITC) LS-C264734

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

EAR2 / NR2F6 Antibody (aa25-53, APC) LS-C264732

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

EAR2 / NR2F6 Antibody (aa25-53, Azide-free, HRP) LS-C264735

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

EAR2 / NR2F6 Antibody (aa25-53, PE) LS-C264737

Antibody:

EAR2 / NR2F6 Rabbit anti-Human Polyclonal (aa25-53) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

EAR2 / NR2F6 Antibody (clone OTI2C9) LS-C340073

Antibody:

EAR2 / NR2F6 Mouse anti-Human Monoclonal (OTI2C9) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

EAR2 / NR2F6 Antibody (clone OTI2H4) LS-C340081

Antibody:

EAR2 / NR2F6 Mouse anti-Human Monoclonal (OTI2H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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