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E2F4

E2F transcription factor 4, p107/p130-binding

E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.

Gene Name: E2F transcription factor 4, p107/p130-binding
Synonyms: E2F4, E2F-4, p107/p130-binding protein, Transcription factor E2F4
Target Sequences: NM_001950 NP_001941.2 Q16254

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Antibodies (50)
Proteins (3)
Over-Expression Lysate (2)
Primary (50)
Recombinant (1)
E2F4 (53)
Human (49)
Mouse (26)
Rat (20)
Bat (3)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (6)
Pig (4)
Rabbit (4)
Zebrafish (3)
IHC (23)
IHC-P (11)
WB (38)
ELISA (14)
ICC (1)
IF (2)
IP (4)
Peptide-ELISA (3)
rabbit (32)
mouse (17)
goat (1)
Product Group
IHCPlus (1)
IgG (27)
IgG1 (4)
IgG1,k (7)
IgG2b (6)
monoclonal mc (17)
polyclonal pc (33)
5B7 (1)
GF1 (1)
OTI10E7 (2)
OTI11H1 (2)
APC Conjugated (3)
Biotin Conjugated (5)
Carrier-free (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (29)
C-Terminus (4)
aa86-413 (4)
Internal (2)
aa363-413 (2)
Leu50/83 (1)
aa228-243 (1)
aa300-350 (1)
aa349-360 (1)
acetylation site of K96. (1)
No (53)
GST (1)
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Purified (1)
E2F4 Antibody - Anti-E2F4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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E2F4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
E2F4 Antibody - Anti-E2F4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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E2F4 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Zebrafish, Rat, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
E2F4 Antibody - Anti-E2F4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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E2F4 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Zebrafish, Rat, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
E2F4 Antibody - Anti-E2F4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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E2F4 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Zebrafish, Rat, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
E2F4 Antibody - Detection of Human E2F4 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-E2F4 used at a dilution of 1:1000 (1 Detection: DAB.
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E2F4 Rabbit anti-Human Polyclonal (aa363-413) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
E2F4 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
E2F4 Antibody - Immunohistochemistry of E2F-4 antibody
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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E2F4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
E2F4 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using E2F4 Antibody. The picture on the right is blocked with the synthesized peptide.
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E2F4 Rabbit anti-Human Polyclonal (Internal) Antibody
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
E2F4 Antibody - E2F4 was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- E2F4 Antigen Affinity purified polyclonal antibody
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E2F4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
E2F4 Antibody - Immunofluorescence staining of E2F4 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human E2F4 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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E2F4 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
E2F4 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using E2F4 antibody.
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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E2F4 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, IP, WB
Unconjugated
200 µg/$832
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E2F4 Mouse anti-Human Monoclonal (GF1) Antibody
Human
IHC, WB
Unconjugated
100 µg/$801
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E2F4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
IHC, WB
Biotin Conjugated
100 µl/$1,027
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E2F4 Mouse anti-Human Monoclonal (FITC) Antibody
Human
IHC, WB
FITC Conjugated
100 µl/$1,027
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E2F4 Mouse anti-Human Monoclonal (PE) Antibody
Human
IHC, WB
PE Conjugated
100 µl/$1,027
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E2F4 Mouse anti-Human Monoclonal (APC) Antibody
Human
IHC, WB
APC Conjugated
100 µl/$1,027
E2F4 Antibody - Immunohistochemistry image of paraffin-embedded human lung tissue at a dilution of 1:100
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E2F4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
E2F4 Antibody - IHC of E2F4/E2F5 (L50/83) pAb in paraffin-embedded human lung carcinoma tissue.
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E2F4 Rabbit anti-Human Polyclonal (Leu50/83) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
E2F4 Antibody - Immunohistochemical analysis of E2F4 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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E2F4 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
E2F4 Antibody - Western blot of COS7 cell lysate using E2F4 Antibody
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
E2F4 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using E2F4 Polyclonal Antibody at dilution of 1:40.
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
E2F4 Antibody - IHC testing of FFPE human intestinal cancer tissue with E2F4 antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
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E2F4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
E2F4 Antibody - E2F4 monoclonal antibody (M01), clone 5B7 Western Blot analysis of E2F4 expression in A-549.
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E2F4 Mouse anti-Human Monoclonal (5B7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Viewing 1-25 of 53 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).