Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MKP3 / DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Anti-DUSP6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4314 concentration 5 ug/ml.
Anti-DUSP6 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4314 concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to DUSP6 on HeLa cell (antibody concentration 10 ug/ml).
Western blot of DUSP6 expression in transfected 293T cell line by DUSP6 monoclonal antibody, clone 3G2.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged DUSP6 is approximately 1 ng/ml as a capture antibody.
Western blot of DUSP6 over-expressed 293 cell line, cotransfected with DUSP6 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with DUSP6 monoclonal antibody clone 3G2. GAPDH ( 36.1 kD ) used as specificity a.
Requested From: United States
Date Requested: 2/19/2017