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Anti-DUSP6 / MKP3 Antibody (clone 3G2) IHC-plus™ LS-B4314

Note: This antibody replaces LS-C104938

Ordering

Wt. Vol. Conc. Price
50 µg - - $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DUSP6 / MKP3 Antibodies

Anti-DUSP6 / MKP3 Antibody (aa14-201) IHC-plus™ LS-B10240
Rabbit Polyclonal to Human DUSP6 / MKP3
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-DUSP6 / MKP3 Antibody LS-C332398
Rabbit Polyclonal (IgG) to Human DUSP6 / MKP3
Human, Mouse, Rat
IHC, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3G2] (IgG1,k) to Human DUSP6 / MKP3
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, RNA interference
Unconjugated

Details

Human DUSP6 / MKP3
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [3G2]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (10 µg/ml)
  • Western blot
  • ELISA
  • RNA interference

Specificity and Use

DUSP6 / MKP3 antibody was raised against dUSP6 (AAH03143, 1 a.a. ~ 382 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Transfected lysate) - positive control transfected 293T cell line. Immunofluorescence (10 ug/ml) - positive control HeLa cells. Sandwich ELISA (Recombinant protein). RNAi Knockdown (Antibody validated).

Packaging

PBS, pH 7.2
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About DUSP6 / MKP3

Q16828 NM_001946 NP_001937.2

DUSP6 Antibody, Dual specificity phosphatase 6 Antibody, MAP kinase phosphatase 3 Antibody, MKP3 Antibody, PYST1 Antibody, RVH6 Antibody, Mapk phosphatase 3 Antibody, MKP-3 Antibody, Phosphatase VH6 Antibody

MKP3 / DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.

Immunohistochemistry

Immunohistochemistry
Anti-DUSP6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4314 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-DUSP6 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4314 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of monoclonal antibody to DUSP6 on HeLa cell (antibody concentration 10 ug/ml).

Western blot

Western blot
Western blot of DUSP6 expression in transfected 293T cell line by DUSP6 monoclonal antibody, clone 3G2.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged DUSP6 is approximately 1 ng/ml as a capture antibody.

RNA interference

RNA interference
Western blot of DUSP6 over-expressed 293 cell line, cotransfected with DUSP6 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with DUSP6 monoclonal antibody clone 3G2. GAPDH ( 36.1 kD ) used as specificity a.

Requested From: United States
Date Requested: 12/5/2016

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