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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DUSP6 / MKP3 Antibody (aa135‑280) LS‑C36214
Antibody
MKP3 antibody LS-C36214 is an unconjugated chicken polyclonal antibody to MKP3 (DUSP6) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C36214-50
50 µg
Unavailable

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Immunohistochemical analysis of DUSP6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry

Product Description

MKP3 antibody LS-C36214 is an unconjugated chicken polyclonal antibody to MKP3 (DUSP6) from human, mouse and rat. Validated for WB.
About DUSP6 / MKP3
MKP3 / DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Q16828 NM_001946 NP_001937.2

DUSP6 Antibody, Dual specificity phosphatase 6 Antibody, MAP kinase phosphatase 3 Antibody, MKP3 Antibody, PYST1 Antibody, RVH6 Antibody, Mapk phosphatase 3 Antibody, MKP-3 Antibody, Phosphatase VH6 Antibody


Specifications

Target
Human DUSP6 / MKP3
Host
Chicken
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgY Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500)
Immunogen
DUSP6 / MKP3 antibody was raised against synthetic peptide corresponding to aa135-280.
Epitope
aa135-280
Specificity
Recognizes human DUSP6a. Species cross-reactivity: Mouse and rat.
Usage
Suitable for use in Western Blot. Western Blot: 1:500. Detects a band of approximately 60 kD in an E-coli fusion protein sample (predicted molecular weight: 42 kD).
Presentation
PBS, pH 7.2, 0.02% sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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