DUSP3 / VHR

dual specificity phosphatase 3

DUSP3 / VHR is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.

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Antibodies (45)

Proteins (12)

ELISA Kits (3)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (45)

Recombinant (10)

Sandwich (2)

Target

DUSP3 / VHR (60)

Reactivity

Human (45)

Mouse (8)

Rat (21)

Bat (1)

Bovine (1)

Hamster (1)

Horse (1)

Monkey (1)

Pig (1)

Sheep (1)

Vaccinia Virus (2)

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Application

IHC (10)

IHC-P (3)

WB (33)

ELISA (18)

ICC (2)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (28)

mouse (17)

Isotype

IgG (27)

IgG1 (1)

IgG1,k (1)

IgG2a (3)

IgG2a,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (17)

polyclonal pc (28)

Clone

2C4 (1)

AT9E6 (1)

OTI2B12 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (2)

APC (2)

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Azide-free (1)

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PE Conjugated (3)

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aa2-185 (18)

C-Terminus (6)

C-terminal (1)

aa1-185 (1)

aa1-30 (1)

aa155-171 (1)

aa2-144 (1)

Publications

No (59)

Yes (1)

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Plasma (2)

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Tag

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (2)

His,N-terminus (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (11)

Source

293T Cells (1)

Baculovirus (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (1)

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DUSP3 / VHR Antibody LS-C76848

Antibody:

DUSP3 / VHR Mouse anti-Vaccinia Virus Monoclonal Antibody

Reactivity:

Vaccinia Virus

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$884

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DUSP3 / VHR Antibody (aa2-185) LS-C293712

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (aa2-185) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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DUSP3 / VHR Antibody (aa2-185, Biotin) LS-C300342

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (aa2-185) (Biotin) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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DUSP3 / VHR Antibody (aa2-185) LS-C314317

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (aa2-185) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296

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DUSP3 / VHR Antibody (aa1-30) LS-C101091

(4.0) Rating

(1) Publication(s)

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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DUSP3 / VHR Antibody (C-terminal) LS-C386989

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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DUSP3 / VHR Antibody (aa1-185) LS-C186048

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (aa1-185) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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DUSP3 / VHR Antibody LS-C76847

Antibody:

DUSP3 / VHR Mouse anti-Vaccinia Virus Monoclonal Antibody

Reactivity:

Vaccinia Virus

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$872

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Human DUSP3 / VHR Protein (Recombinant) (Met1-Pro185) - LS-G98687

Source:

Baculovirus

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.6 kDa

Price:

100 µg/$721

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DUSP3 / VHR Antibody LS-C307323

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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DUSP3 / VHR Antibody LS-C807078

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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DUSP3 / VHR Antibody (C-Terminus) LS-C327228

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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DUSP3 / VHR Antibody (C-Terminus, Biotin) LS-C225201

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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DUSP3 / VHR Antibody (C-Terminus, FITC) LS-C225202

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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DUSP3 / VHR Antibody (C-Terminus, APC) LS-C225199

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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DUSP3 / VHR Antibody (C-Terminus, Azide-free, HRP) LS-C225203

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DUSP3 / VHR Antibody (C-Terminus, PE) LS-C225204

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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DUSP3 / VHR Antibody (clone AT9E6) LS-C755446

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (AT9E6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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DUSP3 / VHR Antibody (Preservative Free) LS-C817967

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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DUSP3 / VHR Antibody (aa2-185, Biotin) LS-C418123

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (aa2-185) (Biotin) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

Biotin Conjugated

Price:

200 µl/$373

Select

DUSP3 / VHR Antibody (aa2-185, FITC) LS-C418124

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (aa2-185) (FITC) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

FITC Conjugated

Price:

200 µl/$388

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DUSP3 / VHR Antibody (aa2-144) LS-C178926

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal (aa2-144) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$332

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DUSP3 / VHR Antibody LS-C743046

Antibody:

DUSP3 / VHR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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DUSP3 / VHR Antibody (clone 2C4) LS-C139514

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (2C4) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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DUSP3 / VHR Antibody (clone OTI2B12) LS-C796482

Antibody:

DUSP3 / VHR Mouse anti-Human Monoclonal (OTI2B12) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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